| Covariate adjusted weighted normal spatial scan statistics with applications to study geographic clustering of obesity and lung cancer mortality in the United States. | |
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MedLine Citation:
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PMID: 20690110 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the field of cluster detection, a weighted normal model-based scan statistic was recently developed to analyze regional continuous data and to evaluate the clustering pattern of pre-defined cells (such as state, county, tract, school, hospital) that include many individuals. The continuous measures of interest are, for example, the survival rate, mortality rate, length of physical activity, or the obesity measure, namely, body mass index, at the cell level with an uncertainty measure for each cell. In this paper, we extend the method to search for clusters of the cells after adjusting for single/multiple categorical/continuous covariates. We apply the proposed method to 1999-2003 obesity data in the United States (US) collected by CDC's Behavioral Risk Factor Surveillance System with adjustment for age and race, and to 1999-2003 lung cancer age-adjusted mortality data by gender in the United States from the Surveillance Epidemiology and End Results (SEER Program) with adjustment for smoking and income. |
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Authors:
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Lan Huang; Ram C Tiwari; Linda W Pickle; Zhaohui Zou |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Statistics in medicine Volume: 29 ISSN: 1097-0258 ISO Abbreviation: Stat Med Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-23 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8215016 Medline TA: Stat Med Country: England |
Other Details:
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Languages: eng Pagination: 2410-22 Citation Subset: IM |
Affiliation:
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Office of Biostatistics, CDER, FDA, Silver Spring, MD 20993, USA. lan.huang@fda.hhs.gov |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Body Mass Index Cluster Analysis Continental Population Groups / statistics & numerical data Female Health Surveys / statistics & numerical data Humans Lung Neoplasms / mortality* Male Middle Aged Models, Statistical Motor Activity Obesity / mortality* SEER Program / statistics & numerical data Smoking / epidemiology United States / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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