Document Detail


Covariate adjusted weighted normal spatial scan statistics with applications to study geographic clustering of obesity and lung cancer mortality in the United States.
MedLine Citation:
PMID:  20690110     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the field of cluster detection, a weighted normal model-based scan statistic was recently developed to analyze regional continuous data and to evaluate the clustering pattern of pre-defined cells (such as state, county, tract, school, hospital) that include many individuals. The continuous measures of interest are, for example, the survival rate, mortality rate, length of physical activity, or the obesity measure, namely, body mass index, at the cell level with an uncertainty measure for each cell. In this paper, we extend the method to search for clusters of the cells after adjusting for single/multiple categorical/continuous covariates. We apply the proposed method to 1999-2003 obesity data in the United States (US) collected by CDC's Behavioral Risk Factor Surveillance System with adjustment for age and race, and to 1999-2003 lung cancer age-adjusted mortality data by gender in the United States from the Surveillance Epidemiology and End Results (SEER Program) with adjustment for smoking and income.
Authors:
Lan Huang; Ram C Tiwari; Linda W Pickle; Zhaohui Zou
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Statistics in medicine     Volume:  29     ISSN:  1097-0258     ISO Abbreviation:  Stat Med     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-23     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8215016     Medline TA:  Stat Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  2410-22     Citation Subset:  IM    
Affiliation:
Office of Biostatistics, CDER, FDA, Silver Spring, MD 20993, USA. lan.huang@fda.hhs.gov
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MeSH Terms
Descriptor/Qualifier:
Adult
Body Mass Index
Cluster Analysis
Continental Population Groups / statistics & numerical data
Female
Health Surveys / statistics & numerical data
Humans
Lung Neoplasms / mortality*
Male
Middle Aged
Models, Statistical
Motor Activity
Obesity / mortality*
SEER Program / statistics & numerical data
Smoking / epidemiology
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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