| Couplings of character and of chirality in the origin of the genetic system. | |
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MedLine Citation:
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PMID: 7693954 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Data from the literature and new data presented here suggest that the genetic system (coding and protein synthesis) is based on relationships of character and structure between amino acids and nucleic acids. Character relationships seem to be anticodonic and structurally the greatest preferences are seen between the heteropair, L-amino acids and D-ribose nucleic acids. However, living systems using the other heteropair must have been equally likely. Homopairing (L-L and D-D) in living systems seems unlikely. Awareness of the heterocoupling of steric forms narrows somewhat the problem of understanding the origin of chirality. |
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Authors:
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J C Lacey; N S Wickramasinghe; G W Cook; G Anderson |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Journal of molecular evolution Volume: 37 ISSN: 0022-2844 ISO Abbreviation: J. Mol. Evol. Publication Date: 1993 Sep |
Date Detail:
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Created Date: 1993-12-10 Completed Date: 1993-12-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0360051 Medline TA: J Mol Evol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 233-9 Citation Subset: IM; S |
Affiliation:
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Biochemistry Department, University of Alabama at Birmingham 35294-2041. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine
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chemistry Amino Acids / chemistry* Anticodon Biogenesis Esterification Genetic Code* Molecular Conformation* Nucleic Acid Conformation Phenylalanine / chemistry RNA / chemistry* Stereoisomerism |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Anticodon; 58-61-7/Adenosine; 63-91-2/Phenylalanine; 63231-63-0/RNA |
| Investigator | |
Investigator/Affiliation:
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J r Lacey JC / U AL, Birmingham |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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