| Coupling glucose fermentation and homoacetogenesis for elevated acetate production: Experimental and mathematical approaches. | |
| | |
MedLine Citation:
|
PMID: 20803563 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
Homoacetogenesis is an important potential hydrogen sink in acetogenesis, in which hydrogen is used to reduce carbon dioxide to acetate. So far the acetate production from homoacetogenesis, especially its kinetics, has not been given sufficient attention. In this work, enhanced production of acetate from anaerobic conversion of glucose through coupling glucose fermentation and homoacetogenesis is investigated with both experimental and mathematical approaches. Experiments are conducted to explore elevated acetate production in a coupled anaerobic system. Acetate production could be achieved by homoacetogenesis with a relative high acetate yield under mixed fermentation conditions. With the experimental observations, a kinetic model is formulated to describe such a homoacetogenic process. The maximum homoacetogenic rate (k(m,homo)) is estimated to be 28.5 ± 1.7 kg COD kg⁻¹ COD day⁻¹ with an uptake affinity constant of 3.7 × 10⁻⁵± 3.1 × 10⁻⁶kg COD m⁻³. The improved calculation of homoacetogenic kinetics by our approach could correct the underestimation of homoacetogenesis in anaerobic fermentation processes, as it often occurs in these systems supported by literature analysis. The model predictions match the experimental results in different cases well and provide insights into the dynamics of anaerobic glucose conversion and acetate production. Furthermore, acetate production via homoacetogenesis increases by about 40% through utilizing the fed-batch coupling system, attributed to a balance between the hydrogen production in the acetogenesis phase and the hydrogen consumption in the homoacetogenesis phase. This work provides an effective way for increased anaerobic acetate production, and gives us a better understanding about the homoacetogenic kinetics in the anaerobic fermentation process. |
| | |
Authors:
|
Bing-Jie Ni; He Liu; Yan-Qiu Nie; Raymond J Zeng; Guo-Cheng Du; Jian Chen; Han-Qing Yu |
Related Documents
:
|
21082303 - Precision of an instrumentation-based method of analyzing occlusion and its resulting d... 22436223 - Impact of production strategies and animal performance on economic values of dairy shee... 17712083 - Multimethod evaluation of information and communication technologies in health in the c... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Biotechnology and bioengineering Volume: 108 ISSN: 1097-0290 ISO Abbreviation: Biotechnol. Bioeng. Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2010-12-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7502021 Medline TA: Biotechnol Bioeng Country: United States |
Other Details:
|
Languages: eng Pagination: 345-53 Citation Subset: IM |
Copyright Information:
|
© 2010 Wiley Periodicals, Inc. |
Affiliation:
|
Department of Chemistry, University of Science & Technology of China, Hefei, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: CHO cell expression, long-term stability, and primate pharmacokinetics and brain uptake of an IgG-pa...
Next Document: Aggregation of bovine anterior cruciate ligament fibroblasts or marrow stromal cells promotes aggrec...