Document Detail

Coupled stochastic resonance to improve chromatography determinations.
MedLine Citation:
PMID:  20052579     Owner:  NLM     Status:  In-Process    
Traditional bistable stochastic resonance has been demonstrated as an effective tool to detect the weak signal in a strong noise background. To achieve a better signal-to-noise ratio for the output signal, a coupled stochastic resonance was developed by nonlinearly coupling two double-well potential systems. The response characteristics of coupled stochastic resonance subjected to analytical signals have been investigated and compared with those of bistable stochastic resonance. The improvement of chromatographic determination with the proposed coupled stochastic resonance was validated by both simulated signals and chromatographic signals. The weak signals from both simulated data and plasma samples with different concentrations were all amplified significantly and the quantitative relationship between different concentrations and responses was kept well. It is reasonable to believe that coupled stochastic resonance could play an important role in applications where quantitative determination of low-concentration samples is crucial.
Shaofei Xie; Bingren Xiang; Haishan Deng; Jingfang Wu
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Publication Detail:
Type:  Journal Article     Date:  2010-01-06
Journal Detail:
Title:  Analytical and bioanalytical chemistry     Volume:  396     ISSN:  1618-2650     ISO Abbreviation:  Anal Bioanal Chem     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-09-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101134327     Medline TA:  Anal Bioanal Chem     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1921-7     Citation Subset:  IM    
Center for Instrumental Analysis, China Pharmaceutical University (Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education), Nanjing, 210009, China.
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