Document Detail

Coupled fluid-structure interaction hemodynamics in a zero-pressure state corrected arterial geometry.
MedLine Citation:
PMID:  21762918     Owner:  NLM     Status:  Publisher    
Hemodynamic conditions in large arteries are significantly affected by the interaction of the pulsatile blood flow with the distensible arterial wall. A numerical procedure for solving the fluid-structure interaction problem encountered in cardiovascular flows is presented. We consider a patient-specific carotid bifurcation geometry, obtained from 3D reconstruction of in vivo acquired tomography images, which yields a geometrical representation of the artery corresponding to its pressurized state. To recover the geometry of the artery in its zero-pressure state which is required for a fluid-structure interaction simulation we utilize inverse finite elastostatics. Time-dependent flow simulations with in vivo measured inflow volume flow rate in the 3D undeformed artery are performed through the finite element method. The coupled-momentum method for fluid-structure interaction is adopted to incorporate the influence of wall compliance in the numerical computation of the time varying flow domain. To demonstrate the importance in recovering the zero-pressure state of the artery in hemodynamic simulations we compute the time varying flow field with compliant walls for the original and the zero-pressure state corrected geometric configurations of the carotid bifurcation. The most important resulting effects in the hemodynamic environment are evaluated. Our results show a significant change in the wall shear stress distribution and the spatiotemporal extent of the recirculation regions.
V Vavourakis; Y Papaharilaou; J A Ekaterinaris
Related Documents :
21762918 - Coupled fluid-structure interaction hemodynamics in a zero-pressure state corrected art...
9187598 - Effects of pentoxifylline on hemodynamics and oxygenation in septic and nonseptic patie...
17993948 - Hemodynamic and oxygen transport patterns after head trauma and brain death: implicatio...
8812258 - Cardiovascular responses to short-term fumonisin exposure in swine.
3655528 - Human endolymphatic sac: possible mechanisms of pressure regulation.
7924128 - Effects of lisinopril and amlodipine on microalbuminuria and renal function in patients...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-13
Journal Detail:
Title:  Journal of biomechanics     Volume:  -     ISSN:  1873-2380     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0157375     Medline TA:  J Biomech     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Institute of Applied and Computational Mathematics, Foundation for Research and Technology-Hellas, Heraklion, Crete 71110, Greece.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Genetical genomics of Th1 and Th2 immune response in a baboon model of atherosclerosis risk factors.
Next Document:  The validity of stability measures: A modelling approach.