| Counting ions around DNA with anomalous small-angle X-ray scattering. | |
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MedLine Citation:
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PMID: 21047071 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The majority of charge-compensating ions around nucleic acids form a diffuse counterion "cloud" that is not amenable to investigation by traditional methods that rely on rigid structural interactions. Although various techniques have been employed to characterize the ion atmosphere around nucleic acids, only anomalous small-angle X-ray scattering (ASAXS) provides information about the spatial distribution of ions. Here we present an experimentally straightforward extension of ASAXS that can be used to count the number of ions around nucleic acids. |
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Authors:
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Suzette A Pabit; Steve P Meisburger; Li Li; Joshua M Blose; Christopher D Jones; Lois Pollack |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-11-03 |
Journal Detail:
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Title: Journal of the American Chemical Society Volume: 132 ISSN: 1520-5126 ISO Abbreviation: J. Am. Chem. Soc. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-18 Completed Date: 2011-03-08 Revised Date: 2011-12-21 |
Medline Journal Info:
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Nlm Unique ID: 7503056 Medline TA: J Am Chem Soc Country: United States |
Other Details:
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Languages: eng Pagination: 16334-6 Citation Subset: IM |
Affiliation:
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School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, United States. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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DNA
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chemistry* Ions Scattering, Small Angle* X-Rays |
| Grant Support | |
ID/Acronym/Agency:
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GM-076121-04S1/GM/NIGMS NIH HHS; GM-085062/GM/NIGMS NIH HHS; GM-088645/GM/NIGMS NIH HHS; R01 GM076121-04S1/GM/NIGMS NIH HHS; R01 GM085062-01A2/GM/NIGMS NIH HHS; R01 GM085062-03/GM/NIGMS NIH HHS; R01 GM088645-01/GM/NIGMS NIH HHS; R01 GM088645-03/GM/NIGMS NIH HHS; T32 GM-008267/GM/NIGMS NIH HHS; T32 GM008267-18/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Ions; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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