Document Detail

Count-rate analysis from clinical scans in PET with LSO detectors.
MedLine Citation:
PMID:  18440959     Owner:  NLM     Status:  MEDLINE    
The purpose of optimising the acquisition parameters in positron emission tomography is to improve the quality of the diagnostic images. Optimisation can be done by maximising the noise equivalent count rate (NECR) that in turn depends on the coincidence rate. For each bed position the scanner records coincidences and singles rates. For each patient, the true, random and scattered coincidences as functions of the single count rate(s) are determined by fitting the NEMA (National Electrical Manufacturers Association) 70 cm phantom count rate curves to measured clinical points. This enables analytical calculation of the personalised PNECR [pseudo NECR(s)] curve, linked to the NECR curve. For central bed positions, missing activity of approximately 70% is estimated to get maximum PNECR (PNECR(max)), but the improvement in terms of signal-toz-noise ratio would be approximately 15%. The correlation between patient weight and PNECR(max) is also estimated to determine the optimal scan duration of a single bed position as a function of patient weight at the same PNEC. Normalising the counts at PNECR(max) for the 70 kg patient, the bed duration for a 90 kg patient should be 230 s, which is approximately 30% longer. Although the analysis indicates that the fast scanner electronics allow using higher administered activities, this would involve poor improvement in terms of NECR. Instead, attending to higher bed duration for heavier patients may be more useful.
F Bonutti; E Cattaruzzi; E Cragnolini; M Floreani; C Foti; M R Malisan; E Moretti; O Geatti; R Padovani
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-04-24
Journal Detail:
Title:  Radiation protection dosimetry     Volume:  129     ISSN:  0144-8420     ISO Abbreviation:  Radiat Prot Dosimetry     Publication Date:  2008  
Date Detail:
Created Date:  2008-07-29     Completed Date:  2008-10-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8109958     Medline TA:  Radiat Prot Dosimetry     Country:  England    
Other Details:
Languages:  eng     Pagination:  288-90     Citation Subset:  IM    
Medical Physics Department, University Hospital, Udine, Italy.
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MeSH Terms
Body Weight
Image Interpretation, Computer-Assisted
Lutetium / diagnostic use*
Phantoms, Imaging
Positron-Emission Tomography / instrumentation*,  methods*
Radiopharmaceuticals / diagnostic use*
Silicates / diagnostic use*
Whole-Body Counting / methods*
Reg. No./Substance:
0/Radiopharmaceuticals; 0/Silicates; 0/lutetium orthosilicate; 7439-94-3/Lutetium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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