Document Detail


Coumarin-induced intramural hematoma of the duodenum: case report and review of the literature.
MedLine Citation:
PMID:  21073371     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Intramural hematoma of the small intestine is a complication of anticoagulant treatment with an estimated incidence of 1 case per 2500 anticoagulated patients per year. Patients may present with signs of small bowel obstruction or, in case of a ruptured hematoma, with upper gastrointestinal tract hemorrhage and hypovolemic shock.
MATERIAL AND METHODS: Case report and review of the literature.
RESULTS: We present a case of a 73-year-old male who was referred for a protruding mass in the duodenum and subsequently developed hematemesis and melena caused by a ruptured hematoma of the duodenal wall.
CONCLUSIONS: Although intramural hematoma of the duodenum is a rare complication of anticoagulant therapy, early diagnosis with subsequent correction of coagulation parameters is of vital importance.
Authors:
Bart J Veldt; Jelle Haringsma; Klaas W Florijn; Ernst J Kuipers
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2010-11-14
Journal Detail:
Title:  Scandinavian journal of gastroenterology     Volume:  46     ISSN:  1502-7708     ISO Abbreviation:  Scand. J. Gastroenterol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-08     Completed Date:  2011-06-06     Revised Date:  2011-11-15    
Medline Journal Info:
Nlm Unique ID:  0060105     Medline TA:  Scand J Gastroenterol     Country:  England    
Other Details:
Languages:  eng     Pagination:  376-9     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, The Netherlands. b.veldt@erasmusmc.nl
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MeSH Terms
Descriptor/Qualifier:
Aged
Anticoagulants / adverse effects*
Coumarins / adverse effects*
Duodenum / drug effects*,  pathology
Gastrointestinal Hemorrhage / chemically induced*,  diagnosis
Hematemesis / chemically induced
Hematoma / chemically induced*,  diagnosis
Humans
Male
Melena / chemically induced
Chemical
Reg. No./Substance:
0/Anticoagulants; 0/Coumarins; 91-64-5/coumarin
Comments/Corrections
Comment In:
Scand J Gastroenterol. 2011 Nov;46(11):1399-400   [PMID:  21644848 ]

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