Document Detail


Coumarin Glycosides and Iridoid Glucosides with Neuroprotective Effects from Hydrangea paniculata.
MedLine Citation:
PMID:  23047248     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Five new coumarin glycosides, umbelliferone 7-O-sophoroside (1), umbelliferone 7-O-β-D-glucopyranosyl(1 → 3)-β-D-glucopyranoside (2), umbelliferone 7-O-β-D-glucopyranosyl(1 → 3)-[β-D-apiofuranosyl(1 → 6)]-β-D-glucopyranoside (3), umbelliferone 7-O-β-D-glucopyranosyl(1 → 2)-β-D-apiofuranosyl(1 → 6)-β-D-glucopyranoside (4), and umbelliferone 7-O-β-D-glucopyranosyl(1 → 5)-β-D-apiofuranosyl(1 → 6)-β-D-glucopyranoside (5), and two new iridoid glucosides, 7-O-E-isoferuloyl loganic acid (6) and 7-O-β-D-glucopyranosyl loganin (7), together with eight known compounds (8-15) were isolated from the stems of Hydrangea paniculata. Their structures were established by spectroscopic analysis and chemical methods. At 10 µM, compounds 1, 3, 5, 6, 8, 9, and 13 showed neuroprotective effects against serum deprivation-induced PC12 cell damage.
Authors:
Jing Shi; Chuang-Jun Li; Jing-Zhi Yang; Yu-He Yuan; Nai-Hong Chen; Dong-Ming Zhang
Related Documents :
23937308 - X-ray absorption spectroscopy proves the trigonal-planar sulfur-only coordination of co...
16209508 - Maldi tof mass study on oligomerization of pd(oac)2(l)2 (l = pyridine derivatives): rel...
10825968 - Disiloxane-protected 2-deoxyribonolactone as an efficient precursor to 1,2-dideoxy-1-be...
20209578 - Modified [(ipr)pd(r-acac)cl] complexes: influence of the acac substitution on the catal...
16504388 - Kinetics of decolorization of an azo dye in uv alone and uv/h(2)o(2) processes.
23282798 - In situ supported mno(x)-ceo(x) on carbon nanotubes for the low-temperature selective c...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-9
Journal Detail:
Title:  Planta medica     Volume:  -     ISSN:  1439-0221     ISO Abbreviation:  Planta Med.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0066751     Medline TA:  Planta Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Georg Thieme Verlag KG Stuttgart · New York.
Affiliation:
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The occurrence and representation of three-centre two-electron bonds in covalent inorganic compounds...
Next Document:  Effect of costunolide and dehydrocostus lactone on cell cycle, apoptosis, and ABC transporter expres...