Document Detail


Could it be Henoch-Schonlein purpura?
MedLine Citation:
PMID:  19458803     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Henoch-Schönlein purpura is the most common form of systemic vasculitis in the paediatric setting with 90% of cases occuring in childhood. Although diagnosis in the primary care setting may be difficult, it is vital in order to avoid significant complications. OBJECTIVE: This article outlines the pathogenesis, clinical manifestations and classification of Henoch-Schönlein purpura and details evidence based investigations and management. DISCUSSION: Henoch-Schönlein purpura is a self limiting disease characterised by a tetrad of clinical manifestations that vary in occurrence and order of presentation. There is no single diagnostic test to confirm Henoch- Schönlein purpura; diagnosis depends on recognition of clinical manifestations. Management usually occurs in the ambulatory setting and is mainly supportive. Priorities include symptom relief and preventive therapy to reduce the risk of complications. Further trials to clarify the role of glucocorticosteroids are needed before a definitive role for steroids in the management of Henoch-Schönlein purpura can be established.
Authors:
Danforn C E Lim; Lisa N C Cheng; Felix W S Wong
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Australian family physician     Volume:  38     ISSN:  0300-8495     ISO Abbreviation:  Aust Fam Physician     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-21     Completed Date:  2009-07-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0326701     Medline TA:  Aust Fam Physician     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  321-4     Citation Subset:  IM    
Affiliation:
Integrative Medicine Research, School of Medicine, Sydney, University of Notre Dame Australia. celim@unswalumni.com
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MeSH Terms
Descriptor/Qualifier:
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Child
Glucocorticoids / therapeutic use
Humans
Immunoglobulin A / blood
Male
Purpura, Schoenlein-Henoch / blood,  diagnosis*,  drug therapy
Skin / immunology,  pathology
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Glucocorticoids; 0/Immunoglobulin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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