Document Detail


Cough: what's in a name?
MedLine Citation:
PMID:  16816346     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The cough reflex (CR) and the expiration reflex (ER) are two defensive reflexes from the respiratory tract, the latter mainly from the larynx. Both are elicited by mechanical and chemical irritation of the airway mucosa, and are a characteristic of airway diseases, but they have different functions. The CR first draws air into the lungs, to accentuate the subsequent expulsive phase; the ER consists of a strong expiration, to prevent aspiration of material into the lungs. They have different sensory pathways, central nervous circuits, and physiological and pharmacological modulations. In practice, coughing often consists of a combination of the two reflexes, a cough bout, epoch or attack. Articles on cough usually do not distinguish between the two reflexes, or whether the coughs are single events or epochs; they usually only measure frequency of expiratory efforts, and neglect other aspects. Current methods for measuring and assessing cough are described, with indications of when the use of these methods may be important.
Authors:
J Widdicombe; G Fontana
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology     Volume:  28     ISSN:  0903-1936     ISO Abbreviation:  Eur. Respir. J.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-03     Completed Date:  2007-01-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8803460     Medline TA:  Eur Respir J     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  10-5     Citation Subset:  IM    
Affiliation:
University of London, London SW20 8NY, UK. JohnWiddicombeJ@aol.com
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MeSH Terms
Descriptor/Qualifier:
Bronchi / pathology*
Cough / diagnosis*
Humans
Larynx / pathology*
Pulmonary Stretch Receptors / metabolism
Reflex / drug effects,  physiology*
Respiration
Respiratory Physiological Phenomena
Respiratory System
Trachea / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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