Document Detail

Costs and Quality of Life in Diabetic Macular Edema: Canadian Burden of Diabetic Macular Edema Observational Study (C-REALITY).
MedLine Citation:
PMID:  24795818     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Purpose. To characterize the economic and quality of life burden of diabetic macular edema (DME) in Canadian patients. Patients and Methods. 145 patients with DME were followed for 6 months with monthly telephone interviews and medical chart reviews at months 0, 3, and 6. Visual acuity in the worst-seeing eye was assessed at months 0 and 6. DME-related healthcare costs were determined over 6 months, and vision-related (National Eye Institute Visual Functioning Questionnaire) and generic (EQ-5D) quality of life was assessed at months 0, 3, and 6. Results. Mean age of patients was 63.7 years: 52% were male and 72% had bilateral DME. At baseline, visual acuity was categorized as normal/mild loss for 63.4% of patients, moderate loss for 10.4%, and severe loss/nearly blind for 26.2%. Mean 6-month DME-related costs/patient were as follows: all patients (n = 135), $2,092; normal/mild loss (n = 88), $1,776; moderate loss (n = 13), $1,845; and severe loss/nearly blind (n = 34), $3,007. Composite scores for vision-related quality of life declined with increasing visual acuity loss; generic quality of life scores were highest for moderate loss and lowest for severe loss/nearly blind. Conclusions. DME-related costs in the Canadian healthcare system are substantial. Costs increased and vision-related quality of life declined with increasing visual acuity severity.
John R Gonder; Valery M Walker; Martin Barbeau; Nancy Zaour; Bryan H Zachau; James R Hartje; Ruihong Li
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Publication Detail:
Type:  Journal Article     Date:  2014-03-26
Journal Detail:
Title:  Journal of ophthalmology     Volume:  2014     ISSN:  2090-004X     ISO Abbreviation:  J Ophthalmol     Publication Date:  2014  
Date Detail:
Created Date:  2014-05-05     Completed Date:  2014-05-05     Revised Date:  2014-05-07    
Medline Journal Info:
Nlm Unique ID:  101524199     Medline TA:  J Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  939315     Citation Subset:  -    
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