Document Detail

Cost-utility analysis of screening and laser treatment of retinopathy of prematurity.
MedLine Citation:
PMID:  19393519     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Retinopathy of prematurity (ROP) is a major cause of lifelong blindness beginning in infancy. Utility analysis is used to describe the effect of illness and medical intervention on an individual's quality of life during the course of a lifetime. In this study, cost-utility analysis is used to evaluate the cost-effectiveness of both screening and laser photoablation for ROP. METHODS: Data from 2 neonatal intensive care units were recorded for infants screened and treated for ROP between March 4, 2004, and January 5, 2006. The cost model was developed using procedures classified by Current Procedural Terminology and the costs paid for by the Centers for Medicare and Medicaid Services for 2006. Visual acuities were obtained from 10-year post-laser data and from the 10-year post-CRYO-ROP untreated cohort. RESULTS: During the study period, 515 infants received screening and treatment for ROP. They required a mean 3.4 exams per infant; 11.2% received laser photoablation. Mean visual acuities were 0.5 (Snellen 20/40) for laser-treated eyes and 0.20 (Snellen 20/100) for those who did not receive treatment. The cost-effectiveness of screening and laser photoablation of ROP in 2006 is $650/quality-adjusted life years. When discounted 3% per year for the time value of money, the cost is $1,565/ quality-adjusted life years. CONCLUSIONS: The screening and laser photoablation of ROP continue to be extremely cost-effective medical interventions.
Jennifer A Dunbar; Victoria Hsu; Marc Christensen; Bradley Black; Pamela Williams; George Beauchamp
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus     Volume:  13     ISSN:  1528-3933     ISO Abbreviation:  J AAPOS     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-27     Completed Date:  2009-08-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9710011     Medline TA:  J AAPOS     Country:  United States    
Other Details:
Languages:  eng     Pagination:  186-90     Citation Subset:  IM    
Department of Ophthalmology, Loma Linda University, Loma Linda, California 92354, USA.
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MeSH Terms
Birth Weight
Cost-Benefit Analysis
Databases, Factual
Infant, Newborn
Intensive Care, Neonatal
Laser Therapy / economics*
Quality-Adjusted Life Years
Retinopathy of Prematurity* / diagnosis,  economics,  surgery
Retrospective Studies
Vision Screening / economics*
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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