Document Detail


[Cost-effectiveness of vaccinating pregnant women against pandemic influenza in Colombia].
MedLine Citation:
PMID:  22858810     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: Estimating the cost-effectiveness ratio of vaccinating pregnant women against the 2009 pandemic influenza A (H1N1) in Colombia during the second wave of the pandemic.
METHODS: A decision tree was constructed, which simulated the health results (deaths and years of potential life lost [YPLL]) in two cohorts of pregnant women; one vaccinated, the other unvaccinated. The model's parameters were drawn from scientific literature and costs were estimated on the basis of a previous study. Incremental cost-effectiveness ratios (ICER) were calculated.
RESULTS: Vaccinating pregnant women against pandemic flu would have prevented between 4 664 and 15 741 outpatient visits and between 119 and 401 hospitalizations. Between US$ 249 530 and US$ 842 163 in costs of care would have been avoided. For the base scenario, vaccinating pregnant women would be cost-effective (ICER/YPLL avoided US$ 7 657). This ICER was responsive to the disease's fatality rate; vaccina tion would not be cost-effective in Colombia in scenarios with a lower fatality rate.
CONCLUSIONS: Vaccinating pregnant women against pandemic influenza is cost-effective in a scenario with a high mortality rate. The existing evidence that pregnant women are at increased risk of complications and that the vaccine is safe would justify its use in pregnant women.
Authors:
Luz Angela Chocontá-Piraquive; Nelson Alvis Guzmán; Fernando De la Hoz Restrepo
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Revista panamericana de salud pública = Pan American journal of public health     Volume:  31     ISSN:  1680-5348     ISO Abbreviation:  Rev. Panam. Salud Publica     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-08-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9705400     Medline TA:  Rev Panam Salud Publica     Country:  United States    
Other Details:
Languages:  spa     Pagination:  447-53     Citation Subset:  IM    
Affiliation:
Grupo de Epidemiología y Evaluación en Salud Pública, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C., Colombia.
Vernacular Title:
Costo-efectividad de la vacunación contra influenza pandémica en mujeres embarazadas en Colombia.
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