Document Detail

[Cost-effectiveness of vaccinating pregnant women against pandemic influenza in Colombia].
MedLine Citation:
PMID:  22858810     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: Estimating the cost-effectiveness ratio of vaccinating pregnant women against the 2009 pandemic influenza A (H1N1) in Colombia during the second wave of the pandemic.
METHODS: A decision tree was constructed, which simulated the health results (deaths and years of potential life lost [YPLL]) in two cohorts of pregnant women; one vaccinated, the other unvaccinated. The model's parameters were drawn from scientific literature and costs were estimated on the basis of a previous study. Incremental cost-effectiveness ratios (ICER) were calculated.
RESULTS: Vaccinating pregnant women against pandemic flu would have prevented between 4 664 and 15 741 outpatient visits and between 119 and 401 hospitalizations. Between US$ 249 530 and US$ 842 163 in costs of care would have been avoided. For the base scenario, vaccinating pregnant women would be cost-effective (ICER/YPLL avoided US$ 7 657). This ICER was responsive to the disease's fatality rate; vaccina tion would not be cost-effective in Colombia in scenarios with a lower fatality rate.
CONCLUSIONS: Vaccinating pregnant women against pandemic influenza is cost-effective in a scenario with a high mortality rate. The existing evidence that pregnant women are at increased risk of complications and that the vaccine is safe would justify its use in pregnant women.
Luz Angela Chocontá-Piraquive; Nelson Alvis Guzmán; Fernando De la Hoz Restrepo
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Revista panamericana de salud pública = Pan American journal of public health     Volume:  31     ISSN:  1680-5348     ISO Abbreviation:  Rev. Panam. Salud Publica     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-08-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9705400     Medline TA:  Rev Panam Salud Publica     Country:  United States    
Other Details:
Languages:  spa     Pagination:  447-53     Citation Subset:  IM    
Grupo de Epidemiología y Evaluación en Salud Pública, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C., Colombia.
Vernacular Title:
Costo-efectividad de la vacunación contra influenza pandémica en mujeres embarazadas en Colombia.
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