| Cost-effectiveness of a lifestyle intervention in preventing Type 2 diabetes. | |
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MedLine Citation:
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PMID: 22004767 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objectives: Previous research has suggested people with impaired fasting glucose (IFG) are less likely to develop Type 2 diabetes (T2DM) if they receive prolonged structured diet and exercise advice. This study examined the within-trial cost-effectiveness of such lifestyle interventions.Methods: Screen-detected participants with either newly diagnosed T2DM or IFG were randomized 2:1 to intervention versus control (usual care) between February and December 2009, in Norfolk (UK). The intervention consisted of group based education, physiotherapy and peer support sessions, plus telephone contacts from T2DM volunteers. We monitored healthcare resource use, intervention costs, and quality of life (EQ-5D). The incremental cost per quality-adjusted life-year (QALY) gain (incremental cost effectiveness ratio [ICER]), and cost effectiveness acceptability curves (CEAC) were estimated.Results: In total, 177 participants were recruited (118 intervention, 59 controls), with a mean follow-up of 7 months. Excluding screening and recruitment costs, the mean cost was estimated to be £551 per participant in the intervention arm, compared with £325 in the control arm. The QALY gains were -0.001 and -0.004, respectively. The intervention was estimated to have an ICER of £67,184 per QALY (16 percent probability of being cost-effective at the £20,000/QALY threshold). Cost-effectiveness estimates were more favorable for IFG participants and those with longer follow-up (≥4 months) (ICERs of £20,620 and £17,075 per QALY, respectively).Conclusions: Group sessions to prevent T2DM were not estimated to be within current limits of cost-effectiveness. However, there was a large degree of uncertainty surrounding these estimates, suggesting the need for further research. |
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Authors:
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Lisa Irvine; Garry R Barton; Amy V Gasper; Nikki Murray; Allan Clark; Tracey Scarpello; Mike Sampson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of technology assessment in health care Volume: 27 ISSN: 1471-6348 ISO Abbreviation: Int J Technol Assess Health Care Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8508113 Medline TA: Int J Technol Assess Health Care Country: England |
Other Details:
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Languages: eng Pagination: 275-82 Citation Subset: IM |
Affiliation:
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Health Economics Group, Norwich Medical School-University of East Anglia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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