Document Detail

Cost-effectiveness of impedance cardiography testing in uncontrolled hypertension.
MedLine Citation:
PMID:  17086009     Owner:  NLM     Status:  MEDLINE    
To evaluate the short- and long-term cost-effectiveness of impedance cardiography (ICG) testing in uncontrolled hypertensives, we analyzed the Consideration of Noninvasive Hemodynamic Monitoring to Target Reduction of Blood Pressure Levels (CONTROL) trial results that compared the blood pressure-lowering effects of standard vs ICG care. Short-term cost-effectiveness was evaluated as the incremental cost per incremental mm Hg reduced during the trial. Long-term cost-effectiveness was evaluated as incremental cost per quality-adjusted life-year gained over 10 years. ICG care short-term cost-effectiveness was 20 US dollar per incremental mm Hg reduced for systolic blood pressure (vs standard care, 36 US dollar per mm Hg reduced) and 23 US dollar per incremental mm Hg reduced for diastolic blood pressure (vs standard care, 79 US dollar per mm Hg reduced). In the long term, ICG resulted in a 476 US dollar cost savings and 0.109 quality-adjusted life-years gained per patient (-4,371 US dollar per quality-adjusted life-year gained, sensitivity analysis -8,764 to 13,163 US dollar). The use of ICG testing to reduce blood pressure in uncontrolled hypertensive patients is cost-effective from both a short- and long-term perspective.
Carlos M Ferrario; Ronald D Smith;
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Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American heart hospital journal     Volume:  4     ISSN:  1541-9215     ISO Abbreviation:  Am Heart Hosp J     Publication Date:  2006  
Date Detail:
Created Date:  2006-11-06     Completed Date:  2007-05-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101156064     Medline TA:  Am Heart Hosp J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  279-89     Citation Subset:  IM    
Hypertension and Vascular Disease Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
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MeSH Terms
Antihypertensive Agents / economics,  therapeutic use
Blood Pressure / drug effects
Cardiography, Impedance / economics*
Cost-Benefit Analysis
Follow-Up Studies
Hypertension / diagnosis*,  drug therapy,  economics*,  epidemiology,  physiopathology
Middle Aged
Quality-Adjusted Life Years
Risk Factors
Risk Reduction Behavior
Sensitivity and Specificity
Time Factors
Treatment Outcome
United States / epidemiology
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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