| Cost-effectiveness of colorectal cancer screening - an overview. | |
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MedLine Citation:
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PMID: 20833348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There are several modalities available for a colorectal cancer (CRC) screening program. When determining which CRC screening program to implement, the costs of such programs should be considered in comparison to the health benefits they are expected to provide. Cost-effectiveness analysis provides a tool to do this. In this paper we review the evidence on the cost-effectiveness of CRC screening. Published studies universally indicate that when compared with no CRC screening, all screening modalities provide additional years of life at a cost that is deemed acceptable by most industrialized nations. Many recent studies even find CRC screening to be cost-saving. However, when the alternative CRC screening strategies are compared against each other in an incremental cost-effectiveness analysis, no single optimal strategy emerges across the studies. There is consensus that the new technologies of stool DNA testing, computed tomographic colonography and capsule endoscopy are not yet cost-effective compared with the established CRC screening tests. |
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Authors:
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Iris Lansdorp-Vogelaar; Amy B Knudsen; Hermann Brenner |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Best practice & research. Clinical gastroenterology Volume: 24 ISSN: 1532-1916 ISO Abbreviation: Best Pract Res Clin Gastroenterol Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-09-13 Completed Date: 2010-12-07 Revised Date: 2011-08-03 |
Medline Journal Info:
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Nlm Unique ID: 101120605 Medline TA: Best Pract Res Clin Gastroenterol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 439-49 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Public Health, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands. i.vogelaar@erasmusmc.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Capsule Endoscopy
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economics Colonography, Computed Tomographic / economics Colonoscopy / economics Colorectal Neoplasms / diagnosis, economics*, prevention & control Cost-Benefit Analysis / statistics & numerical data, trends* Early Detection of Cancer / economics*, statistics & numerical data, trends* Feces Female Humans Male Mass Screening / economics*, methods, trends* Occult Blood Quality-Adjusted Life Years Sigmoidoscopy / economics |
| Grant Support | |
ID/Acronym/Agency:
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U01 CA097426-05/CA/NCI NIH HHS; U01 CA097426-06/CA/NCI NIH HHS; U01 CA097426-07/CA/NCI NIH HHS; U01 CA097426-08/CA/NCI NIH HHS; U01 CA115953-01/CA/NCI NIH HHS; U01 CA115953-02/CA/NCI NIH HHS; U01 CA115953-03/CA/NCI NIH HHS; U01 CA115953-04/CA/NCI NIH HHS; U01 CA115953-05/CA/NCI NIH HHS; U01-CA-088204/CA/NCI NIH HHS; U01-CA-097426/CA/NCI NIH HHS; U01-CA-115953/CA/NCI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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