Document Detail

Cost-effectiveness of blood cultures for adult patients with cellulitis.
MedLine Citation:
PMID:  10585800     Owner:  NLM     Status:  MEDLINE    
To assess the cost-effectiveness of blood cultures for patients with cellulitis, a retrospective review was conducted of clinical and microbiological data for all 757 patients admitted to a medical center because of community-acquired cellulitis during a 41-month period. Blood cultures were performed for 553 patients (73%); there were a total of 710 blood samples (i.e., a mean of 1.3 cultures were performed per patient). In only 11 cases (2.0%) was a significant patient-specific microbial strain isolated, mainly beta-hemolytic streptococci (8 patients [73%]). An organism that was considered a contaminant was isolated from an additional 20 culture bottles (3. 6%). The cost of laboratory workup of the 710 culture sets was $36, 050. Isolation of streptococci led to a change from empirical treatment with cefazolin to penicillin therapy for 8 patients. All patients recovered. In conclusion, the yield of blood cultures is very low, has a marginal impact on clinical management, and does not appear to be cost-effective for most patients with cellulitis.
B Perl; N P Gottehrer; D Raveh; Y Schlesinger; B Rudensky; A M Yinnon
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  29     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2000-02-24     Completed Date:  2000-02-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1483-8     Citation Subset:  IM    
Infectious Diseases Unit, Shaare Zedek Medical Center, Jerusalem 91031, Israel.
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MeSH Terms
Aged, 80 and over
Bacteremia / economics,  microbiology
Bacteria / isolation & purification
Bacterial Infections / blood,  economics,  microbiology*
Bacteriological Techniques
Cellulitis / blood,  economics,  microbiology*
Clinical Laboratory Techniques / economics,  methods
Cost-Benefit Analysis*
Middle Aged
Retrospective Studies
Staphylococcus aureus / isolation & purification
Streptococcus / isolation & purification

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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