| Cost effectiveness of hypertension treatment based on the measurement of ambulatory blood pressure | |
| | |
MedLine Citation:
|
PMID: 20519859 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In recent years soaring medical costs have become a major social problem in developed countries. Ambulatory blood pressure (ABP) measurements have a stronger predictive power for cardiovascular events than clinic blood pressure (CBP) measurements. Therefore the introduction of ABP measurement for the diagnosis and treatment of hypertension should lead to a decrease in medical expenditure. This study presents calculations of the cost saving and life years associated with changing from CBP to ABP measurement as diagnostic tool. We constructed a Markov model using data from the Ohasama study and a Japanese national database. Study population was 7.042 million individuals aged 40 years and above living in Japan. The introduction of ABP for hypertension would result in a reduction of about 9.48 trillion yen per 10 years. We conducted a sensitivity analysis and found that the introduction of ABP was associated with at least a cost reduction of 47500 billion yen. But it did not provide significant extension of average life years. However the introduction of ABP for hypertension treatment would be a very effective method in perspective of public health because it reduced about 59600 individuals of stroke and about 18900 individuals of death. Given its cost-effectiveness, extensive application of ABP measurement in clinical practice is expected. |
| | |
Authors:
|
Yuichiro Tamaki; Takayoshi Ohkubo; Makoto Kobayashi; Keiko Sato; Masahiro Kikuya; Taku Obara; Hirohito Metoki; Kei Asayama; Takuo Hirose; Kazuhito Totsune; Kazuo Suzuki; Yutaka Imai |
Related Documents
:
|
3071579 - The relationship of plasma renin activity to clinic and ambulatory blood pressure in el... 16542489 - Peripheral arterial blood pressure monitoring adequately tracks central arterial blood ... 3675099 - Ambulatory blood pressure monitoring in patients with panic disorder. 10226229 - Twenty-four-hour ambulatory blood pressure monitoring in the evaluation of antihyperten... 14969469 - Profile analysis of 24-hours measurements of blood pressure. 18692809 - Cardiovascular risk in normal weight, eumenorrheic, nonhirsute daughters of patients wi... 12232879 - Data from frequency-volume charts versus maximum free flow rate, residual volume, and v... 990159 - Cardiovascular effects of labetalol during halothane anaesthesia. 2941539 - The character of the atrial natriuretic response: pressure and volume effects. |
Publication Detail:
|
Type: English Abstract; Journal Article |
Journal Detail:
|
Title: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan Volume: 130 ISSN: 0031-6903 ISO Abbreviation: Yakugaku Zasshi Publication Date: 2010 Jun |
Date Detail:
|
Created Date: 2010-06-03 Completed Date: 2010-08-03 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0413613 Medline TA: Yakugaku Zasshi Country: Japan |
Other Details:
|
Languages: jpn Pagination: 805-20 Citation Subset: IM |
Affiliation:
|
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Blood Pressure Monitoring, Ambulatory / economics* Cost-Benefit Analysis* Female Humans Hypertension / complications, diagnosis, economics*, therapy* Male Markov Chains Middle Aged Stroke / economics, etiology, prevention & control |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: In Vivo Biodistribution for Tumor Targeting of 5-Fluorouracil (5-FU) Loaded N-succinyl-chitosan (Suc...
Next Document: Establishment of a system for early exposure provided by new pharmacists in a hospital.