Document Detail

Cost effectiveness of hypertension treatment based on the measurement of ambulatory blood pressure
MedLine Citation:
PMID:  20519859     Owner:  NLM     Status:  MEDLINE    
In recent years soaring medical costs have become a major social problem in developed countries. Ambulatory blood pressure (ABP) measurements have a stronger predictive power for cardiovascular events than clinic blood pressure (CBP) measurements. Therefore the introduction of ABP measurement for the diagnosis and treatment of hypertension should lead to a decrease in medical expenditure. This study presents calculations of the cost saving and life years associated with changing from CBP to ABP measurement as diagnostic tool. We constructed a Markov model using data from the Ohasama study and a Japanese national database. Study population was 7.042 million individuals aged 40 years and above living in Japan. The introduction of ABP for hypertension would result in a reduction of about 9.48 trillion yen per 10 years. We conducted a sensitivity analysis and found that the introduction of ABP was associated with at least a cost reduction of 47500 billion yen. But it did not provide significant extension of average life years. However the introduction of ABP for hypertension treatment would be a very effective method in perspective of public health because it reduced about 59600 individuals of stroke and about 18900 individuals of death. Given its cost-effectiveness, extensive application of ABP measurement in clinical practice is expected.
Yuichiro Tamaki; Takayoshi Ohkubo; Makoto Kobayashi; Keiko Sato; Masahiro Kikuya; Taku Obara; Hirohito Metoki; Kei Asayama; Takuo Hirose; Kazuhito Totsune; Kazuo Suzuki; Yutaka Imai
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Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan     Volume:  130     ISSN:  0031-6903     ISO Abbreviation:  Yakugaku Zasshi     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-03     Completed Date:  2010-08-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413613     Medline TA:  Yakugaku Zasshi     Country:  Japan    
Other Details:
Languages:  jpn     Pagination:  805-20     Citation Subset:  IM    
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences.
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MeSH Terms
Aged, 80 and over
Blood Pressure Monitoring, Ambulatory / economics*
Cost-Benefit Analysis*
Hypertension / complications,  diagnosis,  economics*,  therapy*
Markov Chains
Middle Aged
Stroke / economics,  etiology,  prevention & control

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