Document Detail


Cost-effective and rapid blood analysis on a cell-phone.
MedLine Citation:
PMID:  23392286     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We demonstrate a compact and cost-effective imaging cytometry platform installed on a cell-phone for the measurement of the density of red and white blood cells as well as hemoglobin concentration in human blood samples. Fluorescent and bright-field images of blood samples are captured using separate optical attachments to the cell-phone and are rapidly processed through a custom-developed smart application running on the phone for counting of blood cells and determining hemoglobin density. We evaluated the performance of this cell-phone based blood analysis platform using anonymous human blood samples and achieved comparable results to a standard bench-top hematology analyser. Test results can either be stored on the cell-phone memory or be transmitted to a central server, providing remote diagnosis opportunities even in field settings.
Authors:
Hongying Zhu; Ikbal Sencan; Justin Wong; Stoyan Dimitrov; Derek Tseng; Keita Nagashima; Aydogan Ozcan
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Lab on a chip     Volume:  13     ISSN:  1473-0189     ISO Abbreviation:  Lab Chip     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-05     Completed Date:  2013-08-29     Revised Date:  2014-04-10    
Medline Journal Info:
Nlm Unique ID:  101128948     Medline TA:  Lab Chip     Country:  England    
Other Details:
Languages:  eng     Pagination:  1282-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Blood Cell Count / economics*,  instrumentation*
Blood Chemical Analysis / economics*,  instrumentation*
Cell Count
Cellular Phone*
Cost-Benefit Analysis
Erythrocyte Count
Hemoglobins / analysis
Humans
Leukocyte Count
Point-of-Care Systems
Time Factors
Grant Support
ID/Acronym/Agency:
DP2 OD006427/OD/NIH HHS; DP2OD006427/OD/NIH HHS
Chemical
Reg. No./Substance:
0/Hemoglobins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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