| Cost-effective diagnosis of deep vein thrombosis and pulmonary embolism. | |
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MedLine Citation:
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PMID: 11487038 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Suspected acute venous thromboembolism is a frequent and challenging clinical problem. Phlebography and pulmonary angiography are costly and invasive and, hence, ill-suited for diagnosing a disease present in only 20% of patients in whom it is suspected. Novel noninvasive instruments, such as plasma D-dimer measurement, lower limb compression ultrasonography and helical CT scan are important breakthroughs in the management of patients with suspected venous thromboembolism. However, none of these instruments is ideal, and they must be combined in rational and cost-effective diagnostic algorithms including clinical assessment, which is increasingly standardized. Such strategies must be validated in management studies, in which patients without venous thromboembolism are not treated and followed up during 3 months. Suspected massive pulmonary embolism is a distinct clinical situation requiring a specific diagnostic approach, in which echocardiography plays a major role. This paper reviews the performance of clinical evaluation and diagnostic tests for venous thromboembolism, and recently validated diagnostic schemes. |
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Authors:
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A Perrier; H Bounameaux |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Thrombosis and haemostasis Volume: 86 ISSN: 0340-6245 ISO Abbreviation: Thromb. Haemost. Publication Date: 2001 Jul |
Date Detail:
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Created Date: 2001-08-06 Completed Date: 2002-01-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7608063 Medline TA: Thromb Haemost Country: Germany |
Other Details:
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Languages: eng Pagination: 475-87 Citation Subset: IM |
Affiliation:
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Medical Clinic 1, Department of Internal Medicine, Geneva University Hospital, Switzerland. Arnaud.Perrier@medecine.unige.ch |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Cost-Benefit Analysis Diagnostic Imaging / economics, standards Electrocardiography / economics, standards Humans Pulmonary Embolism / diagnosis*, economics Reagent Kits, Diagnostic / economics, standards Venous Thrombosis / diagnosis*, economics |
| Chemical | |
Reg. No./Substance:
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0/Reagent Kits, Diagnostic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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