Document Detail

Cost-benefit and cost-effectiveness of the incorporation of the pneumococcal 7-valent conjugated vaccine in the routine vaccination schedule of Catalonia (Spain).
MedLine Citation:
PMID:  15755625     Owner:  NLM     Status:  MEDLINE    
The health and economic costs and benefits of vaccinating a cohort of 60,000 children born in Catalonia in the year 2000 with the pneumococcal 7-valent conjugated vaccine were compared with the alternative of not implementing the vaccination programme. The time horizon fixed for the programme was 10 years for invasive disease, 2 years for all episodes of pneumonia and otitis media and 3.5 years for the placement of tympanostomy tubes. In the base case (incidence rate of invasive disease of 160 per 100,000 and price of the vaccine 50 euros) the net present value was negative, both from the societal perspective (-5.1million euros) and from the provider's perspective (-9.2million euros). The benefit-cost ratio was 0.59 euros from the societal perspective. The cost per disability adjusted life year (DALY) gained was 44,307 euros from the societal perspective and 80,291 euros from the provider's perspective.
E Navas; L Salleras; R Gisbert; A Domínguez; E Timoner; D Ibáñez; A Prat
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Vaccine     Volume:  23     ISSN:  0264-410X     ISO Abbreviation:  Vaccine     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-09     Completed Date:  2005-05-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8406899     Medline TA:  Vaccine     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  2342-8     Citation Subset:  IM    
General-Directorate of Public Health, Department of Health, Generalitat of Catalonia, Travessera de les Corts, 131-159, 08028 Barcelona, Spain.
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MeSH Terms
Child, Preschool
Cohort Studies
Cost-Benefit Analysis
Immunization Schedule
Otitis Media / economics,  epidemiology,  prevention & control
Pneumococcal Infections / economics,  epidemiology,  mortality,  prevention & control
Pneumococcal Vaccines / administration & dosage*,  economics*
Pneumonia, Pneumococcal / economics,  epidemiology,  mortality,  prevention & control
Spain / epidemiology
Vaccines, Conjugate / administration & dosage,  economics
Reg. No./Substance:
0/Pneumococcal Vaccines; 0/Vaccines, Conjugate

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