Document Detail


Cost of bacterial vaginosis in pregnancy. Decision analysis and cost evaluation of a clinical study in Germany.
MedLine Citation:
PMID:  10509306     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To estimate the economic impact of screening for and treatment of bacterial vaginosis during early pregnancy. STUDY DESIGN: Data from a clinical study that aligned two screening and treatment strategies and a no-screening or treatment strategy with three gynecologic practices in Berlin were used in decision tree analysis. Costs applied to the clinical outcomes were determined from standard German references and the charges from university clinics. RESULTS: Practices A and B screened all 600 patients in the early second trimester and treated the positive cases with clindamycin 2% vaginal cream (A) or a Lactobacillus preparation (B), which incurred lower total costs, $493,159 and $497,619, as compared to practice C (total costs, $534,926), which did not screen or treat for bacterial vaginosis. Including costs of screening and treatment, the net savings of practice A as compared to practice C was estimated to be $47,316. CONCLUSION: The presence of more preterm, premature and low-birth-weight infants added costs for practice C. The estimated cost savings lend support to the value of screening and treatment for bacterial vaginosis in early pregnancy.
Authors:
E Müller; K Berger; N Dennemark; M Oleen-Burkey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  44     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-10-29     Completed Date:  1999-10-29     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  807-14     Citation Subset:  IM    
Affiliation:
Thomas D. Szucs Medical Economics Research Group, Munich, Germany.
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MeSH Terms
Descriptor/Qualifier:
Administration, Intravaginal
Anti-Bacterial Agents / administration & dosage,  therapeutic use
Clindamycin / administration & dosage,  therapeutic use
Costs and Cost Analysis
Female
Germany
Gestational Age
Humans
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Lactobacillus
Obstetric Labor, Premature / etiology,  prevention & control
Pregnancy
Pregnancy Complications, Infectious / diagnosis,  economics*,  therapy
Vaginosis, Bacterial / complications,  economics*,  therapy
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 18323-44-9/Clindamycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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