Document Detail


Cosmeceuticals for the attenuation of extrinsic and intrinsic dermal aging.
MedLine Citation:
PMID:  18404867     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Since the term "cosmeceutical" was coined over 2 decades ago, the number of products in this category that claim to combat dermal aging has grown dramatically. Topical retinoids remain the mainstay for treating photoaging given their proven efficacy in both clinical and histologic outcomes. In addition to retinoids, many other cosmeceutical agents are now available. The proliferation of products can cause confusion among consumers, who often ask their dermatologist for advice as to which antiaging products they should choose. Ideally, the antiaging claims of cosmeceutical formulations and their components should be demonstrated in controlled clinical trials. In order to provide appropriate recommendations to their patients, dermatologists must become familiar with the available data on currently marketed products and gain experience with antiaging regimens. This review discusses the efficacy of a number of currently marketed drug products with proven photoaging benefits and cosmeceutical products that claim similar benefits. Among the agents discussed are single-entity and combination products containing hydroquinones, retinoids, topical antioxidants, and minerals.
Authors:
Suzanne Bruce
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  7     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-04-14     Completed Date:  2008-05-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  s17-22     Citation Subset:  IM    
Affiliation:
Suzanne Bruce and Associates, PA, USA.
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MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Antioxidants / administration & dosage,  therapeutic use
Benzoquinones / administration & dosage,  therapeutic use
Cosmetics / administration & dosage,  therapeutic use*
Dermatologic Agents / administration & dosage,  therapeutic use*
Drug Combinations
Humans
Hydroquinones / administration & dosage,  therapeutic use
Retinoids / administration & dosage,  therapeutic use
Skin Aging / drug effects*
Tretinoin / administration & dosage,  therapeutic use
Ubiquinone / analogs & derivatives
Chemical
Reg. No./Substance:
0/Antioxidants; 0/Benzoquinones; 0/Cosmetics; 0/Dermatologic Agents; 0/Drug Combinations; 0/Hydroquinones; 0/Retinoids; 123-31-9/hydroquinone; 1339-63-5/Ubiquinone; 302-79-4/Tretinoin; 58186-27-9/idebenone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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