| Cosegregation of hypertrophic cardiomyopathy and a fragile site on chromosome 16 in a large Italian family. | |
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MedLine Citation:
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PMID: 2359098 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied the karyotypes of 10 members of a family in whom hypertrophic cardiomyopathy is segregating as an autosomal dominant trait. In all those affected by the disease, a fragile site on the long arm of chromosome 16 was found, expressed with different frequencies, but the unaffected family members did not show this trait. |
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Authors:
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M Ferraro; G Scarton; M Ambrosini |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of medical genetics Volume: 27 ISSN: 0022-2593 ISO Abbreviation: J. Med. Genet. Publication Date: 1990 Jun |
Date Detail:
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Created Date: 1990-07-27 Completed Date: 1990-07-27 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985087R Medline TA: J Med Genet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 363-6 Citation Subset: IM |
Affiliation:
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Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, Rome, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cardiomyopathy, Hypertrophic / genetics*, mortality Child Chromosome Banding Chromosome Fragile Sites Chromosome Fragility* Chromosomes, Human, Pair 16* Crossing Over, Genetic Gene Frequency* Humans Incidence Italy Karyotyping Middle Aged Pedigree |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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