| Corticotropin-releasing factor: effects on the autonomic nervous system and visceral systems. | |
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MedLine Citation:
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PMID: 2981744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Corticotropin-releasing factor (CRF) acts within the central nervous system to modify the activity of the sympathetic and parasympathetic nervous systems, cardiovascular function, endocrine-pancreatic function, and carbohydrate metabolism. These changes in animal physiology induced by CRF provide a tenable basis for hypothesizing that this peptide may be physiologically involved in integrating the neuroendocrine, autonomic, cardiovascular, and metabolic responses to stressful stimuli. This hypothesis is supported by studies demonstrating that glucocorticoids or CRF receptor antagonists alter both the neuroendocrine and autonomic responses to stress. |
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Authors:
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M R Brown; L A Fisher |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Federation proceedings Volume: 44 ISSN: 0014-9446 ISO Abbreviation: Fed. Proc. Publication Date: 1985 Jan |
Date Detail:
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Created Date: 1985-02-28 Completed Date: 1985-02-28 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372771 Medline TA: Fed Proc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 243-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Medulla
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drug effects Adrenocorticotropic Hormone / blood Angiotensin II / pharmacology Animals Autonomic Nervous System / drug effects*, physiology Blood Pressure / drug effects Cardiovascular System / drug effects Corticosterone / pharmacology Corticotropin-Releasing Hormone / pharmacology*, physiology Dogs Epinephrine / blood Heart Rate / drug effects Hyperglycemia / chemically induced Norepinephrine / blood Rats Sympathetic Nervous System / drug effects |
| Grant Support | |
ID/Acronym/Agency:
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AM26741/AM/NIADDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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11128-99-7/Angiotensin II; 50-22-6/Corticosterone; 51-41-2/Norepinephrine; 51-43-4/Epinephrine; 9002-60-2/Adrenocorticotropic Hormone; 9015-71-8/Corticotropin-Releasing Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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