| Corticosteroid-binding globulin in preterm infants in an intensive care unit. | |
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MedLine Citation:
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PMID: 8582714 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Blood concentration of corticosteroid-binding globulin (CBG) was measured in 85 preterm (24-36 weeks of gestational age) infants over the first 6 weeks of postnatal life. CBG concentrations directly correlated to gestational age and postnatal age in the first week of life. There was a significant increase in CBG values over the first 6 weeks such that mean values at weeks 4 through 6 were significantly greater than values at weeks 1 and 2. Postnatal CBG values were significantly lower in infants who had pulmonary disease during week 1 (p = 0.001). In summary, CBG values were directly correlated to gestational and postnatal age, and negatively correlated to acute illness. We speculate that the lower CBG values with lung disease may reflect an ongoing inflammatory response. |
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Authors:
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S M Scott; L Wells |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Hormone research Volume: 44 ISSN: 0301-0163 ISO Abbreviation: Horm. Res. Publication Date: 1995 |
Date Detail:
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Created Date: 1996-03-21 Completed Date: 1996-03-21 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0366126 Medline TA: Horm Res Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 218-21 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Children's Hospital of New Mexico, University of New Mexico School of Medicine, Albuquerque 87123-5311, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aging
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blood Analysis of Variance Female Gestational Age Humans Infant Infant, Newborn Infant, Premature / blood* Infant, Premature, Diseases / blood* Intensive Care Units, Neonatal Lung Diseases / metabolism Male Regression Analysis Transcortin / metabolism* |
| Grant Support | |
ID/Acronym/Agency:
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5M01RR00997-14-18/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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9010-38-2/Transcortin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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