| Corticosteroid Rotation to Alleviate Dexamethasone-Induced Hiccup: A Case Series at a Single Institution. | |
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MedLine Citation:
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PMID: 21924583 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Dexamethasone, one of the key medications for the prevention of chemotherapy-induced nausea and vomiting (CINV), may cause hiccups as an adverse effect. In this case series, we present five patients who developed hiccups after receiving dexamethasone for CINV. We successfully switched dexamethasone to an equipotent dosage of either methylprednisolone or prednisolone, which resolved the hiccups while maintaining adequate control of CINV. This was achieved without changing the rest of the antiemetic regimen, chemotherapy doses, or the use of other medications such as baclofen, haloperidol, and metoclopramide for hiccups. Further studies on switching dexamethasone to alternative corticosteroids in patients developing hiccups after administration of dexamethasone are warranted. |
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Authors:
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Jung Hun Kang; David Hui; Moon Jin Kim; Hoon Gu Kim; Myoung Hee Kang; Gyeong-Won Lee; Eduardo Bruera |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-15 |
Journal Detail:
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Title: Journal of pain and symptom management Volume: - ISSN: 1873-6513 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8605836 Medline TA: J Pain Symptom Manage Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Internal Medicine, Institute of Health Science, School of Medicine, Gyeongsang National University, Jinju, Republic of Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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