Document Detail


Cortical responses of infants with and without a genetic risk for dyslexia: I. Age effects.
MedLine Citation:
PMID:  10321457     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied auditory event-related potentials (ERP) in newborns and 6-month-old infants, about half of whom had a familial risk for dyslexia. Syllables varying in vowel duration were presented in an oddball paradigm, in which ERPs to deviating stimuli are assumed to reflect automatic change detection in the brain. The ERPs of newborns had slow positive deflections typical of their age, but significant stimulus and group effects were found only by the age of 6 months. In both groups, the responses to the deviant /ka/ were more positive than those to the standard /kaa/ stimuli, contrary to the findings of adult ERPs to duration changes. The results also suggested differences in brain activation pattern between the groups.
Authors:
E Pihko; P H Leppänen; K M Eklund; M Cheour; T K Guttorm; H Lyytinen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuroreport     Volume:  10     ISSN:  0959-4965     ISO Abbreviation:  Neuroreport     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-06-23     Completed Date:  1999-06-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9100935     Medline TA:  Neuroreport     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  901-5     Citation Subset:  IM    
Affiliation:
Department of Psychology, University of Jyväskylä, Finland.
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation / methods
Aging / physiology*
Cerebral Cortex / physiology*
Dyslexia / genetics*
Evoked Potentials, Auditory / physiology*
Humans
Infant
Infant, Newborn
Phonetics
Reference Values
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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