| Cortical lens opacities in the young patient--an indication for a lipogram? | |
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MedLine Citation:
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PMID: 11455719 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To determine the characteristics and prevalence of lenticular opacification in patients with underlying dyslipidaemia. METHODS: Eighty patients of both genders and all ages (18-90 years) were enrolled in the trial if they met the inclusion criteria for dyslipidaemia. Patients were included if their fasting serum cholesterol and triglyceride concentrations were > 5.2 mmol/l and > 2.3 mmol/l, respectively, when measured on three separate occasions over a 1-month period. Patients were excluded if they suffered from any condition known to cause or predispose them to elevated lipid levels or lenticular opacification. Lenticular changes were assessed by means of a slit-lamp through the fully dilated pupil and other physical signs were documented subsequent to thorough physical evaluation. RESULTS: In addition to the classic clinic signs of dyslipidaemia, 31% of patients had cortical lens opacities. Cortical opacities were twice as prevalent as Achilles tendon thickening (16.3%) in our study, the second most prevalent sign of elevated lipid levels. In the subgroup of patients aged under 50 years, 55% had lenticular opacities, predominantly cortical (80%). CONCLUSIONS: Cortical lens opacification was the most prevalent sign of dyslipidaemia and it occurred at a relatively young age in our trial population in those patients who were affected. Cortical lenticular opacification should be regarded as an indication for blood lipid profile evaluation. |
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Authors:
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D Meyer; F J Maritz; P H Liebenberg; D P Parkin; L J Burgess |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde Volume: 91 ISSN: 0256-9574 ISO Abbreviation: S. Afr. Med. J. Publication Date: 2001 Jun |
Date Detail:
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Created Date: 2001-07-17 Completed Date: 2001-08-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404520 Medline TA: S Afr Med J Country: South Africa |
Other Details:
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Languages: eng Pagination: 520-4 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of Stellenbosch and Tygerberg Hospital, W Cape. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Distribution Age Factors Aged Aged, 80 and over Case-Control Studies Cataract / epidemiology, etiology* Causality Female Humans Hyperlipidemias / blood, complications*, diagnosis* Male Mass Screening Middle Aged Ophthalmoscopy Patient Selection* Prevalence |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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