| Cortical correlates of the basic and first harmonic frequency of Parkinsonian tremor. | |
| | |
MedLine Citation:
|
PMID: 19748827 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: It has been hypothesized that the basic and first harmonic frequency of Parkinsonian tremor are somewhat independent oscillations the biological basis of which remains unclear. METHODS: We recorded 64-channel EEG in parallel with EMG of the forearm muscles most affected by rest tremor in 21 PD patients. EMG power spectrum, corticomuscular coherence spectra and EEG power spectra for each EEG electrode were calculated. The dynamics of the coherence and relative EMG and EEG power at the basic (tremor) frequency were calculated by a sliding, overlapping window analysis. Corticomuscular delays and direction of interaction were analysed by the maximizing coherence method for narrow band signals. RESULTS: The contralateral EEG electrodes with maximal coherence were different for the basic and first harmonic frequency. The dynamical coherence curves showed non-parallel time courses for the two frequencies. The mean EEG-EMG and EMG-EEG delays were all around 15-20ms but significantly longer for the first harmonic than for the basic frequency. CONCLUSIONS: Our data indicate different cortical representations and corticomuscular interaction of the basic and first harmonic frequencies of Parkinsonian tremor. SIGNIFICANCE: Separate central generators seem to contribute to the tremor via different pathways. Further studies on this complex tremor network are warranted. |
| | |
Authors:
|
Jan Raethjen; R B Govindan; M Muthuraman; Florian Kopper; Jens Volkmann; Günther Deuschl |
Related Documents
:
|
18003557 - Analysis of heart rate variability using time-varying frequency bands based on respirat... 11782857 - Force/shortening-frequency relationship in multicellular muscle strips and single cardi... 4044367 - Heart beat interoception: a study of individual differences. 10332107 - Human responses to upright tilt: a window on central autonomic integration. 6666617 - Cortical magnification factor and contrast sensitivity to luminance-modulated chromatic... 2930427 - The visually guided control of simulated altitude. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-09-12 |
Journal Detail:
|
Title: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Volume: 120 ISSN: 1872-8952 ISO Abbreviation: Clin Neurophysiol Publication Date: 2009 Oct |
Date Detail:
|
Created Date: 2009-10-26 Completed Date: 2009-11-17 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100883319 Medline TA: Clin Neurophysiol Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 1866-72 Citation Subset: IM |
Affiliation:
|
Department of Neurology, University of Kiel, Schittenhelmstr. 10, 24105 Kiel, Germany. j.raethjen@neurologie.uni-kiel.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Cerebral Cortex / physiopathology* Electroencephalography Electromyography Female Functional Laterality / physiology Humans Male Middle Aged Muscle, Skeletal / physiology* Parkinson Disease / physiopathology* Signal Processing, Computer-Assisted Tremor / physiopathology* |
| Comments/Corrections | |
Comment In:
|
Clin Neurophysiol. 2009 Oct;120(10):1766-7
[PMID:
19748310
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Low resolution electromagnetic tomography analysis of ictal EEG patterns in mesial temporal lobe epi...
Next Document: EEG differences in children between eyes-closed and eyes-open resting conditions.