Document Detail

Corrosion resistance and biocompatibility of a new porous surface for titanium implants.
MedLine Citation:
PMID:  16324146     Owner:  NLM     Status:  MEDLINE    
Alterations of the commercially pure titanium (cpTi) surface may be undertaken to improve its biological properties. The aim of this study was to investigate the biocompatibility of cpTi when submitted to a new, porous titanium, surface treatment (porous Ti). Five types of surface treatments, namely sintered microspheres porous titanium (porous Ti), titanium plasma spray (TPS), hydroxyapatite (HA), sandblasted and acid etched (SBAE), and resorbable blast medium, sandblasted with hydroxyapatite (RBM) were made. In the experimental methods, the corrosion potentials were measured over time, and then a linear sweep voltammetric analysis measured the polarization resistances and corrosion currents. For biocompatibility evaluation, MG63 osteoblast-like cells were used. Cell morphology, cell proliferation, total protein content, and alkaline phosphatase (ALP) activity were evaluated after 2 h, and after 2, 4 and 7 d. Porous Ti and SBAE showed a better corrosion resistance, with a weak corrosion current and a high polarization resistance, than the other surfaces. Cell attachment, cell morphology, cell proliferation, and ALP synthesis were influenced by the surface treatments, with a significant increase observed of the activity of osteoblast cells on the porous coating (porous Ti). Based on these results, it is suggested that the porous Ti surface has a significantly better biocompatibility than the other surface treatments and an excellent electrochemical performance.
Michael Simon; Christelle Lagneau; Jos? Moreno; Michele Lissac; Francis Dalard; Brigitte Grosgogeat
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of oral sciences     Volume:  113     ISSN:  0909-8836     ISO Abbreviation:  Eur. J. Oral Sci.     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-12-05     Completed Date:  2007-12-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504563     Medline TA:  Eur J Oral Sci     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  537-45     Citation Subset:  D; IM    
LEIBO, University Lyon 1, Facult? d'Odontologie, Rue Guillaume Paradin, Lyon Cedex 08, France.
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MeSH Terms
Analysis of Variance
Cell Adhesion
Cell Line, Tumor
Coated Materials, Biocompatible / chemistry*
Osseointegration / physiology
Osteoblasts / cytology,  physiology*
Prostheses and Implants*
Statistics, Nonparametric
Surface Properties
Titanium / chemistry*
Reg. No./Substance:
0/Coated Materials, Biocompatible; 7440-32-6/Titanium

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