| Corrosion behavior and cytotoxicity of Mg-35Zn-3Ca alloy for surface modified biodegradable implant material. | |
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MedLine Citation:
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PMID: 22287336 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This study was conducted to investigate the biocompatibility of Mg-Zn-Ca ternary alloy as a biodegradable material. The casting alloy underwent anodization in an alkaline electrolyte at current density 300 mA/cm(2) and frequency 50 Hz to obtain porous oxide layer. Plasma anodization film using pulse was shown to form irregular porous oxide film. As a result of corrosion test, the corrosion current was shown to decrease and the corrosion voltage was shown to increase in the anodized group, which showed the improvement of corrosion resistance after surface treatment. Sodium silicate (0.1 M) was directly oxidized due to high charges caused by spark and then formed SiO(2) , and the compounds produced inside the film were shown MgO, Mg(2) SiO(4) , and SiO(2.) In the histological examination in rats, all samples of the untreated group were shown to be absorbed 3 weeks later into the body. After the magnesium alloy was implanted, blood vessel expansion and tissue change were shown in the adjacent tissues. However, the changed tissues were shown to return to normal muscle tissues 4 weeks later when the alloy was completely absorbed. These results suggest that anodized Mg-35Zn-3Ca alloy has good biocompatibility in vivo and controls the absorption rate of biomaterials. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012. |
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Authors:
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Ran Sook Park; Yu Kyoung Kim; Sook Jeong Lee; Yong Seok Jang; Il Song Park; Yeo Heung Yun; Tae Sung Bae; Min Ho Lee |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-30 |
Journal Detail:
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Title: Journal of biomedical materials research. Part B, Applied biomaterials Volume: - ISSN: 1552-4981 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101234238 Medline TA: J Biomed Mater Res B Appl Biomater Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Wiley Periodicals, Inc. |
Affiliation:
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Department of Dental Biomaterials and Institute of Oral Bioscience, School of Dentistry and Post BK21 Program, Chonbuk National University, Chonbuk 561-756, South Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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