Document Detail

Correlations of serum lipids, uric acid, and albumin among mothers, offspring, and siblings in Taipei, Taiwan.
MedLine Citation:
PMID:  10910618     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to investigate the correlations of serum lipids, uric acid, and albumin, among mothers (n = 111), offspring (n = 208), and siblings (n = 57) in Taipei, Taiwan. Analytical items included serum triglyceride, serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin. Statistical analysis was performed according to the SAS UNIVARIATE procedure; while regression coefficient, parent-offspring regressions, paired-comparison and heritability were estimated. These results show higher heritabilities of four types of serum lipids, uric acid and albumin between mothers and testers (bYX) or siblings (bZX) by parent-offspring regression analysis. Regression coefficients (bYX) of six characters were significantly different (p < 0.05-0.01). Regression coefficients (bZX) for total cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin were significantly different (p < 0.05-0.01), showing the result of genetic control, because their heritabilities were very high at 0.75-1.0, 0.77-1.0, 0.96-1.0, and 0.48-0.82, respectively. This study disclosed that the serum lipids of children in Taipei, Taiwan were significantly correlated with that of parents, which may be attributed to the result of genetic control.
H H Cheng; S H Yang; C Chen; M S Chiang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi     Volume:  40     ISSN:  1608-8115     ISO Abbreviation:  Acta Paediatr Taiwan     Publication Date:    1999 Jul-Aug
Date Detail:
Created Date:  1999-10-27     Completed Date:  1999-10-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100958202     Medline TA:  Acta Paediatr Taiwan     Country:  CHINA (REPUBLIC : 1949-)    
Other Details:
Languages:  eng     Pagination:  225-32     Citation Subset:  IM    
Department of Nutrition and Health Sciences, Taipei Medical College, Taiwan.
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MeSH Terms
Child, Preschool
Family Health*
Lipids / blood*,  genetics
Serum Albumin / analysis*,  genetics
Uric Acid / blood*
Reg. No./Substance:
0/Lipids; 0/Serum Albumin; 69-93-2/Uric Acid

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