Document Detail

Correlations between M-CHARTS and PHP findings and subjective perception of metamorphopsia in patients with macular diseases.
MedLine Citation:
PMID:  20739469     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess the correlations between a patient's subjective perception of metamorphopsia and the clinical measurements of metamorphopsia by M-CHARTS and PreView PHP (PHP).
METHODS: The authors designed a 10-item questionnaire focusing on the symptoms of metamorphopsia and verified its validity with a Rasch analysis. M-CHARTS measured the minimum visual angle of a dotted line needed to detect metamorphopsia, and PHP used the hyperacuity function for detection. Subjects were 39 patients with idiopathic epiretinal membrane (ERM), 22 patients with idiopathic macular hole (M-hole), 19 patients with age-related macular degeneration (AMD), and 51 healthy controls.
RESULTS: Rasch analysis suggested the elimination of one question. The nine-item questionnaire score significantly correlated to the M-CHARTS score in ERM (r = 0.59; P = 0.0004) but not in M-hole and to the PHP result in AMD (r = -0.29; P = 0.04) but not in ERM. Eighty percent of ERM patients with greater horizontal M-CHARTS score subjectively perceived horizontal metamorphopsia more often. M-CHARTS showed better sensitivities than PHP in both ERM (89% vs. 42%) and AMD (74% vs. 68%) and better specificity (100% vs. 71%) in healthy controls. Rasch analysis indicated that the present form of the questionnaire is better suited for moderate to severe cases of metamorphopsia than for mild cases.
CONCLUSIONS: The questionnaire appears to be a valid assessment of patient subjective perception of metamorphopsia and can be used to supplement the clinical measurements of metamorphopsia by M-CHARTS and PHP in patients with macular diseases.
Eiko Arimura; Chota Matsumoto; Hiroki Nomoto; Shigeki Hashimoto; Sonoko Takada; Sachiko Okuyama; Yoshikazu Shimomura
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies     Date:  2011-01-05
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  52     ISSN:  1552-5783     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-06     Completed Date:  2011-02-07     Revised Date:  2013-01-09    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  128-35     Citation Subset:  IM    
Department of Ophthalmology, Kinki University Faculty of Medicine, Sakai Hospital, Osaka, Japan.
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MeSH Terms
Epiretinal Membrane / diagnosis
Macular Degeneration / diagnosis
Middle Aged
Retinal Diseases / diagnosis*
Retinal Perforations / diagnosis
Sensitivity and Specificity
Sickness Impact Profile*
Vision Disorders / diagnosis*
Vision Tests / instrumentation*
Visual Acuity
Visual Perception*

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