| Correlation of thrombolysis in myocardial infarction (TIMI) risk score with extent of coronary artery disease in patients with acute coronary syndrome. | |
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MedLine Citation:
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PMID: 20225777 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the correlation of thrombolysis in myocardial infarction (TIMI) risk score with extent of coronary artery disease (CAD) in patients with acute coronary syndrome (ACS). METHODS: We conducted a descriptive study among 200 consecutive patients admitted with ACS at Tabba Heart Institute, Karachi from June to December 2008. The TIMI risk score was stratified on seven standard variables. The extent of CAD was evaluated on angiography and significant CAD was defined as > or =70% stenosis in any one of the three major epicardial vessels. RESULTS: The mean age of the sample was 58.53 +/- 10.64 years. Out of 200 patients, there were 142 (71%) patients with TIMI score < or =4 (low and intermediate TIMI risk score) and 58 (29%) patients with TIMI score >4 (high TIMI risk score). Patients with TIMI score >4 were more likely to have significant three vessel CAD (62%) versus those with TIMI risk score <4 (46.2%), (p < 0.04). CONCLUSION: Patients with high TIMI risk score were more likely to have severe multivessel CAD compared with those with low or intermediate TIMI risk score. Hence, patients with TIMI score >4 should be referred for early invasive coronary evaluation to derive clinical benefit. |
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Authors:
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Muhammad Shakir Lakhani; Faisal Qadir; Bashir Hanif; Salman Farooq; Moinuddin Khan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: JPMA. The Journal of the Pakistan Medical Association Volume: 60 ISSN: 0030-9982 ISO Abbreviation: J Pak Med Assoc Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-15 Completed Date: 2010-04-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7501162 Medline TA: J Pak Med Assoc Country: Pakistan |
Other Details:
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Languages: eng Pagination: 197-200 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Tabba Heart Institute, Ziauddin Medical University, Karachi, Pakistan. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Coronary Syndrome
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diagnosis*,
physiopathology Adult Aged Aged, 80 and over Coronary Artery Disease / diagnosis*, physiopathology Coronary Stenosis Cross-Sectional Studies Diabetes Mellitus Female Health Status Indicators Humans Hypertension Male Middle Aged Predictive Value of Tests Risk Assessment Severity of Illness Index Smoking / adverse effects Statistics as Topic Thrombolytic Therapy |
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