Document Detail

Correlation between surface hydrophilicity and osteoblastic differentiation on microgrooved titanium substrata.
MedLine Citation:
PMID:  20553145     Owner:  NLM     Status:  In-Data-Review    
Surface microgrooves and acid etching on titanium (Ti) have been proposed to enhance various cell behaviors. In this study, surface hydrophilicity, protein adsorption, and alkaline phosphatase activity of osteoblasts were analyzed and compared between microgrooved Ti, Ti with microgrooves and further acid etching, smooth Ti, and acid-etched smooth Ti. Correlations between the results of each experiment were analyzed using Pearson's correlation analysis, and the influential factor on alkaline phosphatase activity was determined using multiple stepwise regression analysis. Among groups, the Ti substrata with microgrooves and subsequent acid etching showed significantly greater surface hydrophilicity and alkaline phosphatase activity compared with smooth Ti, whereas the Ti substrata with only microgrooves showed the greatest protein adsorption. Multiple stepwise regression analysis determined the surface hydrophilicity of Ti as the influential factor on alkaline phosphatase activity. This study indicates that surface microgrooves and acid etching on Ti substrata enhance surface hydrophilicity, leading to increased alkaline phosphatase activity.
Suk-Won Lee; Myung-Hyun Lee; Namsik Oh; Jung-Ae Park; Richard Leesungbok; Su-Jin Ahn
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Publication Detail:
Type:  Journal Article     Date:  2010-06-16
Journal Detail:
Title:  The Journal of oral implantology     Volume:  38     ISSN:  0160-6972     ISO Abbreviation:  J Oral Implantol     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-03-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801086     Medline TA:  J Oral Implantol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11-9     Citation Subset:  D    
1  Department of Biomaterials & Prosthodontics, Kyung Hee University Hospital at Gangdong, Institute of Oral Biology, School of Dentistry, Kyung Hee University, Seoul, Republic of Korea.
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