Document Detail


Correlation of splenectomy with portal vein thrombosis in beta-thalassemia major.
MedLine Citation:
PMID:  22355997     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the correlation of portal vein thrombosis and splenectomy in beta-thalassemia major patients visiting Babol Medical University, Iran.
METHODS: This cohort study was done from 1997 to 2008. In our study, major beta-thalassemic patients visiting for transfusion at least once a month at Amirkola Children's Hospital were selected. Portal vein thrombosis was diagnosed through Doppler ultrasound in symptomatic patients. Cases were 160 beta-thalassemia major patients who underwent splenectomy and 160 remaining thalassemic patients without splenectomy were controls. Statistical comparison with Fisher exact test was performed.
RESULTS: Five cases had suffered from portal vein thrombosis (P = 0.03). Majority patients with portal vein thrombosis had their symptoms after first month of the operation.
CONCLUSION: Correlation of splenectomy with portal vein thrombosis is statistically significant among beta-thalassemic children from Iran.
Authors:
Mahmoodi Nesheli Hassan; Galini Moghaddam Tahereb; Tamaddoni Ahmad; Darzi Ali Asghar; Esmaeili Dooki Mohammad Reza; Bijani Ali; Mahmoodi Nesheli Mohsen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  61     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2012-02-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  760-2     Citation Subset:  IM    
Affiliation:
Department of Pediatric Hematology & Oncology, Babol University of Medical Sciences, Babol, Iran.
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