Document Detail


Correlation of residual stenosis immediately after coronary angioplasty with long-term prognosis.
MedLine Citation:
PMID:  9535361     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study evaluated the correlation of residual stenosis after percutaneous transluminal coronary angioplasty with the long-term prognosis. Among consecutive 1,230 patients who underwent coronary angioplasty in the National Cardiovascular Center in Osaka, Japan, 894 patients had de novo lesions. Of these, the 70 patients with acute myocardial infarctions and 105 with unstable angina who had emergency coronary angioplasties were excluded from the study. Among the remaining 719 patients, successful dilatation of the main target vessel was achieved in 592 patients, who then comprised the study group. They were divided into three groups according to their residual stenosis (RS) immediately after coronary angioplasty: group A, RS < 15% (n=208); group B, 15% < or = RS < or = 35% (n=286), and group C, 35% < RS < 50% (n=98). The duration of follow-up was 1,668, 1,660, and 1,680 days in group A, B, and C, respectively. The groups A, B, and C were not significantly different in terms of age, history of myocardial infarction, left ventricular ejection fraction, number of diseased vessels and target vessels, and risk factors such as hypertension, hyperlipidemia, and diabetes mellitus. Primary end point of follow-up was defined as death from any cause and the second end point was occurrence of cardiac events. Kaplan-Meier survival analysis showed significant differences among the three groups. Moreover, survival curves seem to be dependent on the degree of post-procedural residual stenosis. Multivariate analysis using a Cox proportional hazard regression model showed that age, ejection fraction, and residual stenosis were independent determinants of event-free, cardiac, and total survival. Residual stenosis immediately after coronary angioplasty is an independent contributor to long-term clinical prognosis in patients treated with successful balloon coronary angioplasty.
Authors:
S Miyazaki; K Nakao; S Daikoku; A Itoh; Y Miyao; Y Goto; H Nonogi
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Catheterization and cardiovascular diagnosis     Volume:  43     ISSN:  0098-6569     ISO Abbreviation:  Cathet Cardiovasc Diagn     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-06-04     Completed Date:  1998-06-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7508512     Medline TA:  Cathet Cardiovasc Diagn     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  262-70     Citation Subset:  IM    
Affiliation:
Division of Cardiology, National Cardiovascular Center, Suita, Osaka, Japan. smiyazak@hsp.ncvc.go.jp
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Angina, Unstable / complications,  mortality,  radiography,  therapy*
Angioplasty, Transluminal, Percutaneous Coronary*
Coronary Angiography
Coronary Disease / etiology,  mortality,  radiography*
Female
Follow-Up Studies
Humans
Infant, Newborn
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction / complications,  mortality,  radiography,  therapy*
Prognosis
Proportional Hazards Models
Questionnaires
Recurrence
Retrospective Studies
Survival Rate
Time Factors
Comments/Corrections
Comment In:
Cathet Cardiovasc Diagn. 1998 Mar;43(3):271-2   [PMID:  9535362 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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