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Correlation of pulsatility index with intracranial pressure in traumatic brain injury.
MedLine Citation:
PMID:  21534204     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
AIM: In traumatic brain injury (TBI) patients, it is desired to monitor the intracranial pressure (ICP) to assess the cerebral haemodynamics and guide the therapy. The study was designed to see if the pulsatility index (PI) measured by transcranial Doppler ultrasonography (TCD) predicts information about ICP values. MATERIAL and
METHODS: In 52 TBI patients with Glasgow Coma Scale (GCS) score < 9, invasive intracranial monitoring and TCD ultrasonography for PI were performed through five days. ICP, cerebral perfusion pressure (CPP), PI values were recorded and calculated. The correlation and regression analysis between ICP, PI and CPP were investigated in the whole group and in patients with a Glasgow Outcome Score (GOS) of 3-5.
RESULTS: The decline in ICP and PI values was significant through five days. The correlation between ICP and PI was strongly significant (p < 0.0001) on days 1, 3 and 5. In patients with a GOS of 3-5, correlation of ICP and PI was also observed. The only significant correlation observed between CPP and PI was on day 5.
CONCLUSION: The strong correlation observed between ICP and PI through the management period of TBI patients can lead us to use TCD ultrasonography-derived PI as a guide if invasive monitoring is not available.
Authors:
Melek Gura; Ilhan Elmaci; Ramazan Sari; Nilufer Coskun
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Turkish neurosurgery     Volume:  21     ISSN:  1019-5149     ISO Abbreviation:  Turk Neurosurg     Publication Date:  2011  
Date Detail:
Created Date:  2011-05-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9423821     Medline TA:  Turk Neurosurg     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  210-5     Citation Subset:  IM    
Affiliation:
Goztepe Training Hospital, Department of Anesthesiology and Reanimation, Istanbul, Turkey.
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