| Correlation of periscreen strip results and white cell count in peritoneal dialysis peritonitis. | |
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MedLine Citation:
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PMID: 20591004 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Monitoring of peritoneal dialysis (PD) peritonitis can be difficult for visually impaired patients. PeriScreen strips measure leukocyte esterase activity and this might be a useful objective test that can be performed by patients at home. METHODS: A prospective study of 138 episodes of peritonitis was undertaken. Effluent samples were analysed for white cell count (WCC) and PeriScreen score on days 3 and 5. Co-morbidity data were collated from these patients. RESULTS: Effluent WCC and PeriScreen results were found to correlate with the gold standard assessment of microbiology WCC count. A positive PeriScreen result on day 5 predicted that the episode of peritonitis would relapse after treatment with a sensitivity of 80% but with a poor specificity of 45%. Patients who cleared or relapsed their peritonitis could not be differentiated based on their burden of co-morbidity, Karnofsky scores, age, dialysis vintage or infective organism. CONCLUSION: PeriScreen strip analysis correlated with microscopic WCC of PD. However, analysis of PD effluent on day 5 of treatment is not a good test to risk stratify patients for relapsing peritonitis. |
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Authors:
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Stanley Fan; Catherine Lane; Sally Punzalan |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of renal care Volume: 36 ISSN: 1755-6686 ISO Abbreviation: J Ren Care Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-01 Completed Date: 2010-10-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101392167 Medline TA: J Ren Care Country: France |
Other Details:
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Languages: eng Pagination: 90-5 Citation Subset: N |
Affiliation:
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Department of Renal Medicine and Transplantation, The Royal London and St Bartholomew's Hospitals, London, UK. s.fan@qmul.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Carboxylic Ester Hydrolases
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metabolism* Female Great Britain Humans Leukocyte Count* Male Middle Aged Peritoneal Dialysis / adverse effects* Peritonitis / etiology, prevention & control* Predictive Value of Tests Prospective Studies Reagent Strips* Recurrence Self Administration* Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Reagent Strips; EC 3.1.-/leukocyte esterase; EC 3.1.1.-/Carboxylic Ester Hydrolases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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