Document Detail


Correlation of pancreatic enzyme levels with the patient's recovery from acute edematous pancreatitis.
MedLine Citation:
PMID:  1695957     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Levels of total amylase, pancreatic isoamylase, lipase and immunoreactive trypsin were measured in 27 consecutive patients with noncomplicated (methemalbumin negative, no pseudocysts on ultrasound) acute pancreatitis during the acute, subacute, and recovery phases. At the beginning of the recovery phase (no pain, start of oral food intake), amylase and pancreatic isoamylase were below normal, whereas lipase (12% of the patients) and especially trypsin (52% of the patients) were still three times above the upper limit of normal. None of the patients showed a relapse of pain at the time of oral food intake. The conclusion is that amylase and pancreatic isoamylase reflect more accurately the patient's recovery pattern in acute pancreatitis than the other enzymes. Trypsin, however, may be significant in cases of delayed diagnosis. Thus, the decision to start oral food intake should be based on the patient's clinical state rather than on pancreatic enzyme levels.
Authors:
P G Lankisch; H Buschmann-Kaspari; J Otto; K Schröder; H Koop
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Klinische Wochenschrift     Volume:  68     ISSN:  0023-2173     ISO Abbreviation:  Klin. Wochenschr.     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1990-09-04     Completed Date:  1990-09-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985205R     Medline TA:  Klin Wochenschr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  565-9     Citation Subset:  IM    
Affiliation:
Medizinische Abteilung, Städtisches Krankenhaus Lüneburg, Universität Göttingen.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Amylases / blood*
Edema / diagnosis
Female
Follow-Up Studies
Glycoside Hydrolases / blood*
Humans
Isoamylase / blood*
Lipase / blood*
Male
Middle Aged
Pancreas / enzymology*
Pancreatitis / diagnosis*,  enzymology
Trypsin / blood*
Chemical
Reg. No./Substance:
EC 3.1.1.3/Lipase; EC 3.2.1.-/Amylases; EC 3.2.1.-/Glycoside Hydrolases; EC 3.2.1.68/Isoamylase; EC 3.4.21.4/Trypsin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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