| Correlation of neonatal nucleated red blood cell counts in preterm infants with histologic chorioamnionitis. | |
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MedLine Citation:
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PMID: 9240578 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this study was to compare the neonatal nucleated red blood cell counts in preterm infants in the presence and absence of clinical and histologic chorioamnionitis while controlling for gestational age and birth weight percentile. STUDY DESIGN: Nucleated red blood cell counts were obtained from preterm infants delivered after preterm labor or preterm premature rupture of membranes. Patients were divided on the basis of clinical and histologic chorioamnionitis. Nucleated red blood cell counts between groups were compared, and regression analysis controlling for gestational age and birth weight percentile was performed. RESULTS: Of 359 patients, both measures of infection status were significantly associated with increased nucleated red blood cell counts. In the regression analysis histologic chorioamnionitis retained significance, whereas clinical chorioamnionitis did not. CONCLUSIONS: Histologic chorioamnionitis produces an erythropoietic response in the fetus. Whether fetal erythropoiesis is a direct response to mediators of inflammation or whether it is the result of a rise in erythropoietin is unknown. |
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Authors:
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E Leikin; D Garry; P Visintainer; U Verma; N Tejani |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 177 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1997 Jul |
Date Detail:
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Created Date: 1997-08-19 Completed Date: 1997-08-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 27-30 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, New York Medical College, Valhalla 10595, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Birth Weight
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physiology Chorioamnionitis / blood*, pathology Erythrocyte Count Erythropoiesis / physiology Erythropoietin / physiology Female Fetal Blood / cytology* Fetal Membranes, Premature Rupture / complications* Gestational Age Humans Infant, Newborn Infant, Premature / blood*, physiology Obstetric Labor, Premature / complications* Pregnancy Regression Analysis |
| Chemical | |
Reg. No./Substance:
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11096-26-7/Erythropoietin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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