Document Detail

Correlation method versus enhanced modified moving average method for automatic detection of T-wave alternans.
MedLine Citation:
PMID:  20188430     Owner:  NLM     Status:  MEDLINE    
Enhanced modified moving average method (EMMAM) and correlation method (CM) for microvolt TWA identification are compared by aid of simulated ECG tracings (cases of absence of TWA and presence of stationary or time-varying TWA) and ECG recordings from healthy subjects (H-group) and patients who survived an acute myocardial infarction (AMI-group). The two competing methods were found to be equivalent when analyzing clean ECGs affected by stationary TWA. Non-stationary TWA is correctly tracked by the CM, whereas it is identified as stationary by the EMMAM. Moreover, the EMMAM suffers for its tendency to identify as TWA noise and other kinds of repolarization variability. Such limitation is most likely the cause of its false-positive TWA production. Finally, only the CM incorporates a local threshold criterion in the TWA detection algorithm which allows better discrimination between H and AMI groups, who are well known to be at increased risk to develop TWA.
Laura Burattini; Silvia Bini; Roberto Burattini
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-02-25
Journal Detail:
Title:  Computer methods and programs in biomedicine     Volume:  98     ISSN:  1872-7565     ISO Abbreviation:  Comput Methods Programs Biomed     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-15     Completed Date:  2010-06-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8506513     Medline TA:  Comput Methods Programs Biomed     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  94-102     Citation Subset:  IM    
Copyright Information:
2010 Elsevier Ireland Ltd. All rights reserved.
Department of Biomedical, Electronics and Telecommunication Engineering, Polytechnic University of Marche, 60131 Ancona, Italy.
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MeSH Terms
Arrhythmias, Cardiac / diagnosis,  physiopathology*
Case-Control Studies
Computer Simulation
Death, Sudden, Cardiac / pathology,  prevention & control*
Electrocardiography, Ambulatory
Models, Theoretical
Myocardial Infarction / physiopathology
Statistics as Topic
Tachycardia, Ventricular / diagnosis,  physiopathology

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