Document Detail


Correlation of clinical and physiological effects of cerebellar stimulation.
MedLine Citation:
PMID:  6970509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The value of clinical assessment of patients undergoing chronic cerebellar stimulation (CCS) is limited by lack of objective measures but neurophysiological tests can be used to "biocalibrate" the stimulator and may be used to predict effects of CCS. Eighty-seven patients undergoing CCS have been assessed clinically and neurophysiologically over the last 4 years. Somatosensory evoked responses were significantly ( p less than 0.05) reduced in amplitude in 35 patients, cortical somatosensory evoked responses in 44 patients and one or both responses were reduced in 55 patients. There were no clinical or physiological changes in 16 patients. Evoked responses showed significant changes in only 3 patients who did not show clinical improvement. The mean voltage settings were 5.2 volts and most patients were stimulated at 200 herz. These results indicate that significant changes in those somatosensory evoked potentials are a good indication of clinical benefits from CCS but clinical improvement may occur in the absence of any acute effect on evoked responses.
Authors:
I S Cooper; A R Upton; Z H Rappaport; I Amin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurochirurgica. Supplementum     Volume:  30     ISSN:  0065-1419     ISO Abbreviation:  Acta Neurochir Suppl (Wien)     Publication Date:  1980  
Date Detail:
Created Date:  1981-04-24     Completed Date:  1981-04-24     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0140560     Medline TA:  Acta Neurochir Suppl (Wien)     Country:  AUSTRIA    
Other Details:
Languages:  eng     Pagination:  339-44     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cerebellum*
Cerebral Palsy / physiopathology,  therapy*
Electric Stimulation Therapy*
Epilepsy / physiopathology,  therapy*
Evoked Potentials
Female
Humans
Male
Somatosensory Cortex / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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