Document Detail

Correlation of clinical and histopathological with endoscopic findings of celiac disease in the Turkish population.
MedLine Citation:
PMID:  17356915     Owner:  NLM     Status:  MEDLINE    
Endoscopic findings have been described for the diagnosis of celiac disease but the relationship among the clinical presentation, endoscopic markers, and the degree of histopathological findings is not clear. Thirty patients who were thought to have celiac disease were included in this study. Biopsies taken from the duodenum were examined histopathologically. The relationship among the endoscopic, clinical, and histopathological findings were investigated. Partial villous atrophy was seen in 14 patients (46.6%), and subtotal and total villous atrophy were seen in 6 (20%) patients each. Eighty six percent of patients with a mosaic appearance, 76% of patients with the finding of loss of folds, and 90% of patients with scalloping on endoscopy had either partial villous atrophy, subtotal villous atrophy, or total villous atrophy on biopsy. We conclude that endoscopic findings in celiac disease can reveal valuable information both for diagnosis and for demonstration of the severity of the disease state.
Nurten Savas; Sabiye Akbulut; Ulku Saritas; Tankut Koseoglu
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2007-03-14
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  52     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-18     Completed Date:  2007-06-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1299-303     Citation Subset:  AIM; IM    
Department of Gastroenterology, Baskent University Faculty of Medicine, Fevzi Cakmak Cad. 10, Sok No. 45, Bahcelievler, Ankara, 06490, Turkey.
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MeSH Terms
Aged, 80 and over
Celiac Disease / diagnosis*,  pathology,  physiopathology
Duodenum / pathology*,  physiopathology
Intestinal Mucosa / pathology*
Microvilli / pathology
Middle Aged
Predictive Value of Tests
Sensitivity and Specificity
Severity of Illness Index

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