| Correlation of clinical and MRI staging in cervical carcinoma treated with radiation therapy: a single-center experience. | |
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MedLine Citation:
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PMID: 20683815 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE To correlate clinical and MRI findings in patients with cervical carcinoma treated with radiation therapy (RT). MATERIALS AND METHODS Forty-two patients with pretreatment IB-IVA cervical carcinoma were included in this retrospective study. Pre- and post-treatment MRI findings of the patients were reevaluated and compared with clinical staging. Six-month, one-year, and two-year follow-up imaging by MR was performed for 36, 20, and 7 patients, respectively. The correlation between clinical and MRI findings was assessed by a Spearman's rho (rank correlation) test. Univariate analyses were performed to identify the prognostic significance of the tumor volume and lymph node status. RESULTS Pre-treatment correlations between MRI and clinical findings for diagnoses without parametrial invasion, with parametrial invasion, and with pelvic sidewall invasion were 71.0%, 64.7%, and 15.8%, respectively. According to the Spearman's rho (rank correlation) test, the parametrial invasion correlation was poor (r = 0.410, P < 0.01). The correlation of clinical and MRI findings at 6 months was 88.9% (r = 0.674, P < 0.0001). CONCLUSION In advanced cervical cancer, the correlation of clinical and MRI staging prior to neoadjuvant RT was low despite a high correspondence in the assessment of local response after RT. |
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Authors:
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Gülgün Engin; Seden Küçücük; Hatice Olmez; Zehra Işık Haşıloğlu; Rian Dişçi; Işık Aslay |
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Publication Detail:
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Type: Journal Article Date: 2010-08-04 |
Journal Detail:
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Title: Diagnostic and interventional radiology (Ankara, Turkey) Volume: 17 ISSN: 1305-3612 ISO Abbreviation: Diagn Interv Radiol Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101241152 Medline TA: Diagn Interv Radiol Country: Turkey |
Other Details:
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Languages: eng Pagination: 44-51 Citation Subset: IM |
Affiliation:
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From the Department of Radiology, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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