Document Detail


Correlation of chromatic, spatial, and temporal sensitivity in optic nerve disease.
MedLine Citation:
PMID:  1748555     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Spearman rank-order correlations (R) were made between the color-mixture threshold, spatial contrast sensitivity, and flicker sensitivity measurements of 38 patients with a variety of optic nerve disorders. Patients had to satisfy the following criteria: greater than 0.5 log unit loss of chromatic or achromatic sensitivity (compared to age-matched normals), central fixation, no congenital color defects, and no ocular media abnormalities. The results of the analysis show a significant correlation between selective losses of high spatial frequency sensitivity (relative to low) and selective losses of red/green and blue/yellow sensitivities [R = -0.680 (P less than 0.001) and R = -0.439 (P less than 0.01), respectively]. A mild correlation was found between selective spatial and selective temporal losses [r = -0.399 (P less than 0.05)] (ie, low temporal frequency losses correlate with high spatial frequency losses and vice versa). A stronger correlation was found between selective red/green and selective blue/yellow sensitivity losses [R = 0.657 (P less than 0.001)]. No correlation was found between selective temporal losses and selective chromatic losses. These findings can be explained in terms of differential losses of three types of fibers: (1) fibers that are particularly sensitive to red/green color, high spatial and low temporal frequencies; (2) fibers signalling blue/yellow color; and (3) fibers that are relatively sensitive to high temporal frequencies and low spatial frequencies.
Authors:
S S Grigsby; A J Vingrys; S C Benes; P E King-Smith
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  32     ISSN:  0146-0404     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-01-23     Completed Date:  1992-01-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  3252-62     Citation Subset:  IM    
Affiliation:
College of Optometry, Ohio State University, Columbus 43210.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Child
Color Perception / physiology*
Contrast Sensitivity / physiology*
Female
Flicker Fusion / physiology*
Humans
Light
Male
Middle Aged
Nerve Fibers / physiology
Optic Nerve Diseases / physiopathology*
Space Perception / physiology*
Grant Support
ID/Acronym/Agency:
EY 04948/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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