Document Detail

Correlation of change in uterine activity to blood loss in the third stage of labour.
MedLine Citation:
PMID:  9736799     Owner:  NLM     Status:  MEDLINE    
In 47 women, the change in the uterine activity after the administration of a uterotonic agent was correlated with the amount of blood loss during the same period of time. Uterine activity was measured by a Gaeltec catheter-tipped pressure transducer inserted transcervically within 5 min of delivery of the placenta. A uterotonic agent (either intravenous syntocinon, intramuscular syntometrine or oral misoprostol) was given after the insertion of the intrauterine pressure catheter and pressure recorded for another 90 min. Blood loss over the same 2-hour period was collected with absorbent paper which was then assessed by colorimetric measurement of the haemoglobin content in the sample. Our results show that the change in uterine activity is associated with the total blood loss. However, there is a poor linear correlation between the two variables probably because of the biological variation in myometrial activity and differences in coagulation mechanisms in normal women.
W L Choo; S Chua; Y S Chong; K Vanaja; P L Oei; L M Ho; A C Roy; S Arulkumaran
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  46     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1998  
Date Detail:
Created Date:  1998-11-13     Completed Date:  1998-11-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  178-80     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, National University of Singapore National University Hospital, Singapore.
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MeSH Terms
Blood Coagulation
Ergonovine / administration & dosage,  therapeutic use
Hemoglobins / analysis
Labor Stage, Third*
Misoprostol / administration & dosage,  therapeutic use
Oxytocin / administration & dosage,  therapeutic use
Postpartum Hemorrhage / diagnosis*
Transducers, Pressure
Uterus / physiopathology*
Reg. No./Substance:
0/Hemoglobins; 0/Oxytocics; 37209-62-4/syntometrine; 50-56-6/Oxytocin; 59122-46-2/Misoprostol; 60-79-7/Ergonovine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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