Document Detail


Correlation of birthweight with foeto-maternal immunoglobulin, total protein and albumin profile.
MedLine Citation:
PMID:  108945     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Using immunodiffusion and biuret methods, immunoglobulins (GAMD), total proteins and albumin measurements were performed at birth on 100 apparently healthy Nigerian mothers and their babies. Sizeable concentrations of IgG were present at birth even in babies with low birth weights (1360 mg/100 ml). The mean IgG level in babies with low birth weights (2,500 g or less) was significantly lower (P less than 0.05) than in average weight and above average weight babies. The mean maternal and cord IgG levels were approximately equal in all except in the low birth weight babies where the mean maternal level was about 40% higher than the mean cord level. The scatter in IgG values was more pronounced in babies with low birth weights than the others. Mothers with higher IgG levels than in their corresponding babies were most prominent in the 'low birth weight' group. There was no significant difference between the maternal as well as between the cord serum IgA and IgM levels. The mean cord serum IgA and IgM levels were about 4 and 10% respectively of their mothers. Compared with the Caucasians, relatively higher quantities of IgD were found in the Nigerian mothers. Twenty-one percent of the maternal and all the cord sera had no detectable amount of IgD. The mean maternal total proteins though higher than the cord serum proteins, showed no statistical difference. The foeto-maternal serum albumin differential, showed statistical difference when average weight babies and above average weight babies were considered (P less than 0.05) but not with low birth weight babies (P less than 0.2).
Authors:
O A Ladipo; L S Salimonu; B O Osunkoya
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  African journal of medicine and medical sciences     Volume:  7     ISSN:  0309-3913     ISO Abbreviation:  Afr J Med Med Sci     Publication Date:  1978 Dec 
Date Detail:
Created Date:  1979-07-25     Completed Date:  1979-07-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7801013     Medline TA:  Afr J Med Med Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  211-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Birth Weight*
Blood Proteins / analysis*
Female
Fetal Blood / analysis
Humans
Immunoglobulin A / analysis
Immunoglobulin D / analysis
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Infant, Newborn
Serum Albumin / analysis
Chemical
Reg. No./Substance:
0/Blood Proteins; 0/Immunoglobulin A; 0/Immunoglobulin D; 0/Immunoglobulin G; 0/Immunoglobulin M; 0/Serum Albumin

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